I tried multiple options, ending with

WSGIDaemonProcess daemon processes=8 threads=8

where processes was 2x the number of cpus (mutex issues appear to hit
at times)

number of threads didn't seem to affect performance much after 8.

I thought the docs section of the turbogears site ran turbogears -- or
is that mod_python/sphinx doing the ajax search?

In looking at it further, it appears to be an application stack
issue.  SQLAlchemy doesn't quite do things in the most efficient
manner when dealing with backreferences, so, I am probably going to
change things around a little to specify the joins myself.

I guess I need to do a bit of profiling to see where the bottleneck
really is, then, figure out how to engineer around it.

I'll eventually deploy with nginx, but, the webserver/wsgi end doesn't
appear to be the bottleneck.
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