Not in general. Variables change too quickly for that to be viable - think
>>about a loop counter in a while loop, it could change millions of times
>>>>per second!
>>
>>
>Could you not use an observer pattern here to do that?
>
>http://en.wikipedia.org/wiki/Observer_pattern
>
You could but the danger romains that if someone puts the 
change inside a loop:

>
for n in range(10,000):
     ChangeMyVariable()

>
You could wind up getting 10,000 change notifications within a second 
and very few applications will respond nicely to that! Which makes it a 
risky option and using a persistent queue such as a database table or 
middleware queuing mechanism is far safer.

>
HTH,

>
Alan G.
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