Kathryn Joosten didn't begin her career until her 40s (I happened to see her in a Chicago production of "Come Back Little Sheba" in 1982--she was better than the production), but when she moved to LA she became much in demand, playing the secretary on "The West Wing" and winning an Emmy twice for her role as Mrs. McKluskey on "Desperate Housewives"--her death came after a long bout with lung cancer: http://tvline.com/2012/06/02/kathryn-joosten-desperate-housewives-dies-lung-cancer/
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