We've been getting reports from developers that the API has been
suffering from elevated latency, and in some cases have heard of
requests failing completely.
This is clearly a high priority issue, and is being actively
investigated by the team at Twitter HQ.
We'll post updates on Twitter http://twitter.com/twitterapi and to
this mailing list when we have them.
Thank you to all the developers who have provided us with examples and
datasets of where this has happened to them.
Developer Advocate, Twitter