>  1) for Windows platform, is possible to generate one single .exe file
>  taht includes all the required stuff (such as libraries and runtime
>  components)? If not, it is possible to group all of them in one single
>  .zip file?

Look for py2exe, it can convert your .py script into an executable
plus a few DLLs that you can zip up.

>  2) What about serial ports support? Is this really platform independent?
>  3) What about graphical interface? Is it possible to use the same
>  library (and consequently have similar look&feel) on Windows and Linux?

You can look into wxPython for platform-independent GUI

Thanks
Donald

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