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Department of Biomedical Engineering

University of Alberta

jabb...@ualberta.ca<mailto:jabb...@ualberta.ca>

thecobralab.com<https://nam04.safelinks.protection.outlook.com/?url=http%3A%2F%2Fthecobralab.com%2F&data=05%7C02%7Cuai%40engr.oregonstate.edu%7C5dc022b3d7b44a10397008dced57fc60%7Cce6d05e13c5e4d6287a84c4a2713c113%7C0%7C0%7C638646209368796959%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C0%7C%7C%7C&sdata=1ye0O5rg3tM0Zp4yEDAnoLIoa7%2Bvgez%2FuS9V43P8WX8%3D&reserved=0>

Postdoc/PhD positions in saRNA for Vaccine Development


We are seeking applications for multiple Senior Researcher positions, available 
immediately for exceptionally motivated Postdoctoral Fellows or PhD students. 
These positions offer a unique opportunity to contribute to a pioneering 
project applying artificial intelligence and machine learning to the 
development of RNA vaccines against emerging viral threats such as Influenza, 
Lassa, and Orthopox viruses.


Project Overview: This ambitious project utilises self-amplifying RNA (saRNA) 
technology, which offers the potential for more potent immune responses at 
lower doses compared to traditional mRNA vaccines. Our approach focuses on the 
use of structural RNA bioinformatics to design vaccine candidates and predict 
the effects of viral mutations, enhancing our ability to respond rapidly to 
evolving pandemic threats.


Key Responsibilities:


  *   Develop AI-driven models to predict the structural implications of 
mutations in viral proteins, aiding in the rapid design of effective saRNA 
vaccines.

  *   Collaborate closely with a team of world-renowned experts, including 
Nobel laureate Michael Houghton and CIFAR AI Chair Russ Greiner, to integrate 
computational predictions with experimental virology.

  *   Engage in the full cycle of vaccine development, from computational 
design to laboratory validation and pre-clinical testing.


Qualifications:


  *   PhD in Computer Science, Bioinformatics, Computational Biology, or a 
related field, with a strong emphasis on machine learning.

  *   Demonstrated experience in structural bioinformatics or a similar field, 
with a focus on RNA or protein structure prediction.

  *   Proven track record of innovative research and a strong publication 
record in relevant fields.

  *   Excellent communication skills and the ability to work collaboratively in 
an interdisciplinary team.


What We Offer:


  *   An opportunity to work alongside national and international leaders in 
artificial intelligence and virology.

  *   Access to state-of-the-art computational resources and a dynamic research 
environment.

  *   A pivotal role in designing strategies for global health security and 
pandemic response, with the potential to significantly impact public health.


How to Apply: Please submit your CV, copies of your transcripts, a cover letter 
highlighting your research interests and fit for the role, and name and contact 
information of two references to 
jabb...@thecobralab.com<mailto:jabb...@thecobralab.com> with subject line saRNA 
Vaccines by November 15, 2024. Applications are reviewed until the positions 
are filled.

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