I get the same issue in 9.10 karmic koala. Even though I have it set to
"open links in a new tab" in System > Preferences > Preferred
Applications, when I click on a link in thunderbird, it tried to open a
new firefox instance under the same profile and gives me an error.
firefox 3.5.5+nobinonly-0ubuntu0.9.10.1
** Also affects: firefox-3.5 (Ubuntu)
Importance: Undecided
Status: New
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[MASTER]Firefox is already running message
https://bugs.launchpad.net/bugs/308605
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