After following some random links from Launchpad I found this message: https://lists.launchpad.net/duplicity-team/msg02653.html
Which discusses whether setting `GPG_OPTS="--pinentry-mode loopback"` might fix it. I tried that and it does work. I wish this information was easier to find. :( ** Changed in: duply (Ubuntu) Status: New => Invalid -- You received this bug notification because you are a member of Ubuntu Bugs, which is subscribed to Ubuntu. https://bugs.launchpad.net/bugs/1638516 Title: Fatal error with GPG after upgrade to Ubuntu 16.10 To manage notifications about this bug go to: https://bugs.launchpad.net/ubuntu/+source/duply/+bug/1638516/+subscriptions -- ubuntu-bugs mailing list ubuntu-bugs@lists.ubuntu.com https://lists.ubuntu.com/mailman/listinfo/ubuntu-bugs