I have the issue as well. I have a dual boot system with following. 
Zenbook UX490UAR
Ubuntu 18.04.1
Windows 10

I think this is due to windows not properly shutting down and holding on
to a hardware device, although not sure how. Managed to resolve by a
full shutdown. i.e. go to shutdown on the windows start menu and hold
shift while pressing restart. A screen will appear where you can select
to shutdown.

After the restart and logging into ubuntu, sound works . 
For the volume control related bug, there was a guide here : 
https://askubuntu.com/questions/906303/volume-control-on-asus-zenbook-3

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https://bugs.launchpad.net/bugs/1784485

Title:
  [ZenBook S UX391UA, Realtek ALC294, Mic, Internal] No sound at all

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