I got the same issue. "systemctl status systemd-tmpfiles-setupd-dev.service" 
yields the same response. But my system (Ubunutu 18.04.1) is starting properly 
and there are no problems when using it. 
In /var/log/syslog these lines precede the error:
Jan 11 14:37:48 Intel-i5-Tower systemd[1]: Started Apply Kernel Variables.
Jan 11 14:37:48 Intel-i5-Tower systemd-tmpfiles[311]: Unsafe symlinks 
encountered in /dev/cuse, refusing.
Jan 11 14:37:48 Intel-i5-Tower systemd-tmpfiles[311]: Unsafe symlinks 
encountered in /dev/autofs, refusing.
Jan 11 14:37:48 Intel-i5-Tower systemd-tmpfiles[311]: Unsafe symlinks 
encountered in /dev/btrfs-control, refusing.
Jan 11 14:37:48 Intel-i5-Tower systemd-tmpfiles[311]: Unsafe symlinks 
encountered in /dev/userio, refusing.
Jan 11 14:37:48 Intel-i5-Tower systemd-tmpfiles[311]: Unsafe symlinks 
encountered in /dev/vfio, refusing.
Jan 11 14:37:48 Intel-i5-Tower systemd-tmpfiles[311]: Unsafe symlinks 
encountered in /dev/vfio/vfio, refusing.
Jan 11 14:37:48 Intel-i5-Tower systemd-tmpfiles[311]: Unsafe symlinks 
encountered in /dev/vhci, refusing.
Jan 11 14:37:48 Intel-i5-Tower systemd-tmpfiles[311]: Unsafe symlinks 
encountered in /dev/uhid, refusing.
Jan 11 14:37:48 Intel-i5-Tower systemd-tmpfiles[311]: Unsafe symlinks 
encountered in /dev/vhost-net, refusing.
Jan 11 14:37:48 Intel-i5-Tower systemd-tmpfiles[311]: Unsafe symlinks 
encountered in /dev/vhost-vsock, refusing.
Jan 11 14:37:48 Intel-i5-Tower systemd-tmpfiles[311]: Unsafe symlinks 
encountered in /dev/snd, refusing.
Jan 11 14:37:48 Intel-i5-Tower systemd-tmpfiles[311]: Unsafe symlinks 
encountered in /dev/snd, refusing.
Jan 11 14:37:48 Intel-i5-Tower systemd-tmpfiles[311]: Unsafe symlinks 
encountered in /dev/snd/timer, refusing.
Jan 11 14:37:48 Intel-i5-Tower systemd-tmpfiles[311]: Unsafe symlinks 
encountered in /dev/snd/seq, refusing.
Jan 11 14:37:48 Intel-i5-Tower systemd[1]: systemd-tmpfiles-setup-dev.service: 
Main process exited, code=exited, status=1/FAILURE
Jan 11 14:37:48 Intel-i5-Tower systemd[1]: systemd-tmpfiles-setup-dev.service: 
Failed with result 'exit-code'.
Jan 11 14:37:48 Intel-i5-Tower systemd-fsck[584]: Ubuntu/home: sauber, 
316299/66273280 Dateien, 223989723/265086556 Blöcke
Jan 11 14:37:48 Intel-i5-Tower systemd[1]: Failed to start Create Static Device 
Nodes in /dev.
Jan 11 14:37:48 Intel-i5-Tower systemd[1]: Reached target Local File Systems 
(Pre).

Perhaps the error is due to the unsave symlinks?

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https://bugs.launchpad.net/bugs/1807682

Title:
  system does not start

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