Hi @mfo

I still hit this problem on instances running the 3.13.0 Kernel, but on
other instances where I upgraded the Kernel to the HWE Kernel (derived
from Ubuntu 16.04) I no longer have the issue.

It's hard to reproduce, since the problems occur only occasionally and
randomly. Out of 626 processes using bowtie2 I ran in the past half a
year on instances with the 3.13.0 Kernel, 17 crashed, and each of them
successfully completed after retrying the exact same command on a
different EC2 instance with the exact same configuration.

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https://bugs.launchpad.net/bugs/1813018

Title:
  Kernel Oops - unable to handle kernel paging request; RIP is at
  wait_migrate_huge_page+0x51/0x70

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