This looks the same as https://ubuntuforums.org/archive/index.php/t-2330904.html
In summary, this is caused by USB power-saving, and this can be disabled by kernel parameter "usbcore.autosuspend" -- You received this bug notification because you are a member of Ubuntu Bugs, which is subscribed to Ubuntu. https://bugs.launchpad.net/bugs/1904953 Title: USB2.0 HUB only works after an USB device is connected To manage notifications about this bug go to: https://bugs.launchpad.net/ubuntu/+source/linux/+bug/1904953/+subscriptions -- ubuntu-bugs mailing list ubuntu-bugs@lists.ubuntu.com https://lists.ubuntu.com/mailman/listinfo/ubuntu-bugs