What makes urine black in some people?
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April 6, 2004 By C. CLAIBORNE RAY Q. Why does Pepto-Bismol make my tongue turn black a few hours after I take it? A. The active ingredient of this 100-year-old patent medication, first developed to fight the symptoms of a debilitating kind of diarrhea in children called cholera infantum, is now known to be a compound of the element bismuth called bismuth subsalicylate. (The original formula of the forerunner of Pepto-Bismol, which is now made by Procter & Gamble, also contained pepsin, zinc salts, salol - a compound related to aspirin - and oil of wintergreen, along with the familiar pink coloration.) Bismuth has antidiarrheal, antibacterial and antacid effects in the digestive tract. When a small amount of bismuth combines with trace amounts of sulfur in saliva and the gastrointestinal tract, a black-colored substance called bismuth sulfide is formed. The discoloration can last for several days. A black tongue is a harmless side effect, and is so listed in the product's package information. Depending on how much is taken and other factors like age and speed of digestion, Pepto-Bismol can also linger in the system and cause a temporary darkening of the stool, which is also harmless. http://www.nytimes.com/2004/04/06/health/06QNA.html?ex=1082384672&ei=1&en=7c28f68d546a31c8 --------------------------------- Get Home Delivery of The New York Times Newspaper. Imagine reading The New York Times any time & anywhere you like! Leisurely catch up on events & expand your horizons. Enjoy now for 50% off Home Delivery! Click here: http://homedelivery.nytimes.com/HDS/SubscriptionT1.do?mode=SubscriptionT1&ExternalMediaCode=W24AF HOW TO ADVERTISE --------------------------------- For information on advertising in e-mail newsletters or other creative advertising opportunities with The New York Times on the Web, please contact [EMAIL PROTECTED] or visit our online media kit at http://www.nytimes.com/adinfo For general information about NYTimes.com, write to [EMAIL PROTECTED] Copyright 2004 The New York Times Company
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