Waiting times, revascularization modality, and outcomes after acute
myocardial infarction at hospitals with and without on-site
revascularization facilities in Canada*1

David A. Alter MD, PhD, , *, , , Jack V. Tu MD, PhD*, , �, ||, , #,
Peter C. Austin PhD*,  and C. David Naylor MD, DPhil*, , ||, , #

* Institute for Clinical Evaluative Sciences, Toronto, Canada
 Division of Cardiology, Schulich Heart Centre, Sunnybrook and
Women's College Health Sciences Centre and the University of Toronto,
Toronto, Canada
 Faculty of Medicine, University of Toronto, Toronto, Canada

Received 4 November 2002;  revised 20 December 2002;  accepted 6
February 2003. ; Available online 31 July 2003.

Abstract

Objectives

This study was designed to determine whether admission to a Canadian
hospital with on-site revascularization (invasive hospital) affected
revascularization choice, timing, and outcome compared with community
(non-invasive) hospitals.

Background

Health care systems in Canada are characterized by relative restraint
in diffusion of tertiary cardiovascular services, with capacity for
revascularization procedures concentrated in large regional referral
centers.

Methods

We used linked administrative data and a clinical registry to
follow-up 15,166 Ontario patients who underwent revascularization
within the year after their index acute myocardial infarction (MI).
Outcomes included recurrent urgent cardiac hospitalization, hospital
bed-days, and death within the same year after the index admission.
We adjusted for age, gender, socioeconomic status, illness severity,
attending physician specialty, and academic hospital affiliation.

Results

After adjusting for baseline factors, patients admitted to invasive
hospitals were more likely to receive angioplasty than bypass surgery
(adjusted odds ratio: 1.85; 95% confidence interval: 1.68 to 2.04, p
< 0.001). The converse pattern was seen for patients admitted to
community hospitals. Median revascularization waiting times were
significantly shorter at invasive hospitals (12 vs. 48 days, p <
0.001). Patients admitted to invasive hospitals had fewer cardiac
re-admissions (41.5 vs. 68.9 events per 100 patients, p < 0.001)
before their first revascularization and consumed fewer hospital
bed-days (379 vs. 517 per 100 patients, p < 0.001). There were no
differences in outcomes beyond revascularization.

Conclusions
Outcome advantages associated with timely post-MI revascularization
highlight the importance of organizing revascularization referral
networks and facilitating access to revascularization for patients
with acute coronary syndromes admitted to community hospitals in
Canada.







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