IM

J'ob�is aux gwendolines des ANglais, et aux r�cent papier du Canada CMAJ.

Qui citent Simon, Simon, et sans doute Simon et Simon (Joe, Averell, Jack, et  et ... zut !):

 J Allergy Clin Immunol. 2001 Nov;108(5):871-3. 

Epinephrine absorption in adults: intramuscular versus subcutaneous injection.

Simons FE, Gu X, Simons KJ.

Section of Allergy & Clinical Immunology, Department of Pediatrics & Child
Health, Faculty of Medicine, University of Manitoba, Winnipeg, Canada.

We report a prospective, randomized, blinded, placebo-controlled, 6-way
crossover study of intramuscular versus subcutaneous injection of epinephrine in
young men. Peak plasma epinephrine concentrations were significantly higher (P <
.01) after epinephrine was injected intramuscularly into the thigh than after
epinephrine was injected intramuscularly or subcutaneously into the upper arm.
We recommend intramuscular injection of epinephrine into the thigh as the
preferred route and site of injection of this life-saving medication in the
initial treatment of anaphylaxis.

Ceci dit �a ne parait pas le probl�me, le probl�me serait que la voie sous-cut expose � des retards, plut�t q u'� de moindres pics.



Message du 25/08/03 16:51
De : Catherine Bich <[EMAIL PROTECTED]>
A : URG-L Mailing List <[EMAIL PROTECTED]>
Copie � :
Objet : URG-L: epinephrine







Donnez-vous l'�pi 1:1000 s/c ou IM en cas
d'anaphylaxie? Para�trait que IM est plus efficace?

 

Quels sont vos habitudes � cet �gard?

 

C.



Axel Ellrodt
Essonne, France
http://zzorglub.ifrance.com/
A website for emergency physicians
Azee'iil'inaa biwebsite
Honlap oxyologusok szamara

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