More support for chest-compression-only resuscitation for out-of-hospital
cardiac arrest
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Dec 14, 2007       <http://www.theheart.org/images/article_datedivemail.gif>
Steve Stiles    

Dallas, TX - Two observational studies published online by Circulation this
week concluded that the conventional method of cardiopulmonary resuscitation
(CPR) that calls for mouth-to-mouth assisted ventilation is no more
effective than a chest-compression-only approach [1, 2]. The findings
support a good deal of international research supporting use of the latter
method, which is less complicated and may be more appealing to potential
bystander rescuers. 

In their retrospective analysis of almost 10 000 cases of bystander
resuscitation for cardiac arrest in which one or the other method was used
[1], Katarina Bohm (Karolinska Institute, South General Hospital Stockholm,
Sweden) and colleagues saw no significant difference in the odds that the
victim would survive to be hospitalized or in one-month survival. 

The findings support the use of the "simpler version of CPR," which can be
especially useful "in dispatcher-assisted CPR and in cases involving elderly
bystanders, in which the simplest algorithm is probably also the best," the
group writes. 

They point to "two large, independent, prospective, randomized trials"
comparing the two methods that are ongoing in the US, in Finland, and in
Sweden. "We therefore suggest waiting for the results of these randomized
trials before starting any new discussion to change guidelines."

In the longer-term prospective study of about 4900 cases of witnessed
out-of-hospital arrests by Dr Taku Iwami (National Cardiovascular Center,
Suita, Japan) and associates [2], the chances of one-year-survival with
"favorable" neurologic outcomes was similarly increased with either method,
compared with no bystander resuscitation-by 72% using the compression-only
or "cardiac-only" technique, and by 57% with standard CPR.

"If cardiac-only resuscitation is simply as effective as conventional CPR,
is there any reason to change lay CPR programs to focus on cardiac-only
resuscitation? Perhaps," the group writes.

"Conventional CPR is a complex psychomotor task, and it typically is
provided for <25% of out-of-hospital arrests," observe Iwami et al.
"Specific educational campaigns to teach cardiac-only resuscitation may
increase the rate of bystander CPR and improve the quality of cardiac-only
resuscitation, thereby improving survival from out-of-hospital cardiac
arrest.

Circulation posted the two studies online December 10, 2007; both are
scheduled for its December 18/25, 2007 issue.

Dr Gordon A Ewy (University of Arizona College of Medicine, Tucson), a
longtime advocate of chest-compression-only resuscitation [3], who wasn't
associated with either study, said that no randomized trial is needed for
the technique to be recommended. 

He pointed out to heartwire that the most current guidelines, published in
2005 [4], had updated the conventional-CPR recommended ratio from 15 chest
compressions to two ventilations to 30 chest compressions to two
ventilations. Whether 15 or 30 compressions, he said, the guidelines were
based on consensus, not data. 

But Ewy's group recently published data in a pig model suggesting that the
continuous-compression technique, which he calls "cardiocerebral
resuscitation," yields better outcomes than 30:2 CPR [5]. That, combined
with the abundant supporting observational data, he said, showed that
bystander CPR improves survival, and survival is better using the
compression-only method. 

"There's no question in my mind that the guidelines need to change, and they
need to change now," Ewy said.

In Bohm et al's analysis of 8902 cases of out-of-hospital standard CPR and
1145 cases of compression-only resuscitation, 19.6% and 20% of patients,
respectively, made it to the hospital alive; the adjusted odds ratio (OR)
for CPR vs chest-compression-only was 1.03 (95% CI, 0.86-1.23). The
one-month survival rates were 7.2% for standard CPR and 6.7% for the simpler
technique (adjusted OR, 1.18 [95% CI, 0.89-1.56]).

In the prospective, population-based study of 4902 witnessed cardiac arrests
in Japan, there were 783 cases in which bystanders performed conventional
CPR and 544 in which only chest compressions were used; there were no
bystander attempts in the remainder. Excluding arrests lasting >15 minutes,
the one-year rate of survival with favorable neurologic outcomes was 4.1%
for standard CPR, 2.5% for no resuscitation (OR 1.57 [95% CI, 0.95-2.60]),
and 4.3% for compression only (OR 1.72 [95% CI, 1.01-2.95]). 

Ewy, like Iwami et al, observes that regardless of inherent efficacy, the
compression-only method is likely to save more lives than standard CPR, if
only because it's more likely to be carried out. "People are afraid of
getting an infection, or they just don't like doing mouth-to-mouth on a
stranger, or they don't know how or are afraid they'll do harm. For whatever
reason, it's being done in only one out of five cases in certain societies,
and two out of five in others," according to Ewy. "And if you just call 911
and don't do anything until the paramedics get there, you might as well sign
the patient's death certificate."


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Sources 
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1.      Bohm K, Rosenqvist M, Herlitz J, et al. Survival is similar after
standard treatment and chest compression only in out-of-hospital bystander
cardiopulmonary resuscitation. Circulation. Published online before print
December 10, 2007.
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_u
ids=18071077&dopt=Abstract>    <http://www.theheart.org/images/pixel.gif> 

2.      Iwami T, Kawamura T, Hiraide A, et al. Effectiveness of
bystander-initiated cardiac-only resuscitation for patients with
out-of-hospital cardiac arrest. Circulation. Published online before print
December 10, 2007.
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_u
ids=18071072&dopt=Abstract>    <http://www.theheart.org/images/pixel.gif> 

3.      Be a lifesaver with continuous chest compression CPR tutorial.
University of Arizona Sarver Heart Center. Available at
http://www.heart.arizona.edu/publiced/lifesaver.htm
<http://www.theheart.org/viewDocument.do?document=http%3A%2F%2Fwww.heart.ari
zona.edu%2Fpubliced%2Flifesaver.htm> .
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4.      ECC Committee, Subcommittees and Task Forces of the American Heart
Association. 2005 American Heart Association guidelines for cardiopulmonary
resuscitation and emergency cardiovascular care. Circulation 2005;
112:IV1-IV203.
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_u
ids=16314375&dopt=Abstract>    <http://www.theheart.org/images/pixel.gif> 

5.      Ewy GA, Zuercher M, Hilwig RW, et al. Improved neurological outcome
with continuous chest compressions compared with 30:2
compressions-to-ventilations cardiopulmonary resuscitation in a realistic
swine model of out-of-hospital cardiac arrest. Circulation 2007;
116:2525-2530.
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_u
ids=17998457&dopt=Abstract>    <http://www.theheart.org/images/pixel.gif> 

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