Le Wednesday 03 September 2008 09:43:04 dominic larose, vous avez écrit :
> Alain a raison, comme d'habitude.
> Mais le tx de l'HTA est bien pour la prévention de l'AVC. Sauf que la
> populace et plusieurs md pensent que cela prévient l'AVC du jour même ou du
> lendemain, alors qu'il prévient l'AVC dans qq années. Concernant les IM, il
> y a beaucoup moins de stemi, mais plus de nstemi je crois, a cause de ces
> tx préventifs. Dominic Larose

Une petite recherche rapide dans Dynamed. Quelques citations intéressantes. 
J'aime bien la deuxième...

1...risk of stroke is much more responsive to treatment than risk of heart 
disease greater reductions in systolic blood pressure associated with lower 
risk of stroke, independent of medications used to lower blood pressure 
(level 1 [likely reliable] evidence); based on meta-analysis of meta-analysis 
of > 40 randomized trials (Stroke 2004 Mar;35(3):776)

2...patients ≥ 80 years old with higher blood pressure (up to 139/89 mmHg) 
less likely to die than patients with lower blood pressure in retrospective 
cohort study of 4,071 ambulatory patients ≥ 80 years old with hypertension, 
follow-up 5 years (J Am Geriatr Soc 2007 Mar;55(3):383), commentary can be 
found in Am Fam Physician 2008 Jan 1;77(1):94, J Am Geriatr Soc 2007 Dec;55
(12):2102

3...lowering blood pressure over 3-5 years effective in preventing severe 
disease progression, left ventricular hypertrophy, and congestive heart 
failure; meta-analysis of 12 long-term placebo-controlled hypertension 
treatment trials with 26,731 patients, most using initial diuretic therapy 
then beta-blockers; prior meta-analysis showed treatment to reduce stroke by 
38% and coronary disease mortality by 16% (J Am Coll Cardiol 1996 Apr;27:1214 
in QuickScan Reviews in Fam Pract 1996 Sep;21(6):16)

4....home blood pressure but not office blood pressure predicted 
cardiovascular mortality in 4,939 treated hypertensive elderly (mean age 70 
years) (level 1 [likely reliable] evidence) (JAMA 2004 Mar 17;291(11):1342), 
commentary can be found in J Fam Pract 2004 Oct;53(10):832, commentary can be 
found in Am Fam Physician 2004 Oct 15;70(8):1558

5...moderate alcohol consumption (> 10 g/day) associated with reduced risk for 
myocardial infarction but non-significant increased risk for stroke in 
prospective cohort of 11,711 men with hypertension (Ann Intern Med 2007 Jan 
2;146(1):10), editorial can be found in Ann Intern Med 2007 Jan 2;146(1):65, 
commentary can be found in Am Fam Physician 2007 Oct 15;76(8):1208

-- 
Martin Chénier
[EMAIL PROTECTED]

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