Hi,

I am using the v3.2.2 ctakes.
I copied the v3.2.1.1 resources.

I used another tool for extracting chemical/drug entities and when processing 
my input text, I got the following results:
1092   1107   nucleotide 1517
1165   1178   aspartic acid
1184   1191   glycine
1195   1204   codon 506
1254   1257   Asp

My input test text is :
A novel missense mutation Asp506Gly in Exon 13 of the F11 gene in an 
asymptomatic Korean woman with mild factor XI deficiency. Factor XI (FXI) 
deficiency is a rare autosomal recessive coagulation disorder most commonly 
found in Ashkenazi and Iraqi Jews, but it is also found in other ethnic groups. 
It is a trauma or surgery-related bleeding disorder, but spontaneous bleeding 
is rarely seen. The clinical manifestation of bleeding in FXI deficiency cases 
is variable and seems to poorly correlate with plasma FXI levels. The molecular 
pathology of FXI deficiency is mutation in the F11 gene on the chromosome band 
4q35. We report a novel mutation of the F11 gene in an 18-year-old asymptomatic 
Korean woman with mild FXI deficiency. Pre-operative laboratory screen tests 
for lipoma on her back revealed slightly prolonged activated partial 
thromboplastin time (45.2 sec; reference range, 23.2-39.4 sec). Her FXI 
activity (35%) was slightly lower than the normal FXI activity (reference 
range, 50-150%). Direct sequence analysis of the F11 gene revealed a 
heterozygous A to G substitution in nucleotide 1517 (c.1517A>G) of exon 13, 
resulting in the substitution of aspartic acid with glycine in codon 506 
(p.Asp506Gly). To the best of our knowledge, the Asp506Gly is a novel missense 
mutation, and this is the first genetically confirmed case of mild FXI 
deficiency in Korea.

When I start the same treatment using ctakes and the 
AggregatePlaintextFastUMLSProcessor annotator file.

No drug entity is detected inside drugner leaf (
[cid:[email protected]]
For example I would have thought that nucleotide be classified in the drugner 
leaf.

Please could you correct me if I missed anything ?

Christian

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