Heather,
Yes, the 114 samples are from their "discovery" studies (24 samples) and "prevalence" studies (the rest of them). Jason ________________________________ From: [email protected] [mailto:[email protected]] On Behalf Of Estrella, Heather Sent: Monday, March 21, 2011 11:38 AM To: Elena Rivkin; [email protected] Subject: Re: [BioMart Users] ICGC BioMart: Pancreatic Cancer (JHU/US) dataset reference Thanks Elena, That's the reference I was thinking the data was probably from. The total number of samples used for genetic analysis in this study was 24 not 114. Can you please look into correcting the summary stats so that the correct frequency is reported for mutations? In looking at the sample names for this study in BioMart, it looks like additional studies were added to the BioMart dataset. Maybe that's where the n-114 came from. However, that messes up the frequencies as not all the genes were tested in all 114 samples. Many thanks, Heather From: Elena Rivkin [mailto:[email protected]] Sent: Monday, March 21, 2011 9:14 AM To: Estrella, Heather; [email protected] Subject: Re: [BioMart Users] ICGC BioMart: Pancreatic Cancer (JHU/US) dataset reference Heather, These data were derived from the following publication: Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses Siân Jones1,* et al. Science. 2008 September 26; 321(5897): 1801-1806. doi:10.1126/science.1164368. Elena From: "Estrella, Heather" <[email protected]<mailto:[email protected]>> Date: Mon, 21 Mar 2011 12:08:21 -0400 To: "[email protected]<mailto:[email protected]>" <[email protected]<mailto:[email protected]>> Subject: [BioMart Users] ICGC BioMart: Pancreatic Cancer (JHU/US) dataset reference Hi, In looking at the mutation frequencies reported for the Pancreatic Cancer (JHU/US) dataset, it reports the frequencies out of n=114. Can you please send me the reference to the source data behind what's reported for "Pancreatic Cancer (JHU/US)"? Thanks, Heather
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