hi 
you can add exception handler on route or context scope to send the nac
reply , as for ack after sending the jms you can create the ack message and
post it to tcp point 

e.g .


from direct
{onexception 
create nak response ,attach it to exchange body 
to tcp
}

to jms 
ceate ack response and attach it to exchange body 
to tcp





-----
Othman Darwish
ProgressSoft Corp.

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