Mark,
I will start  with simple flow diagrams and user cases.
If you more a visual person you can use some mock-ups to help you to orientate 
your project goal.
Don't try to do everything in one step. Set milestones for your project.

For the technical side:
UISERVER (Back end + DB)
Choose your technologies and frame works that will help achieve your goal.
For the UI side i prefer MVC. But, you should choose the one that fits you 
better or your team.

For a good project I like to use this keywords:SOLIDKISSDRY
When we respect this basis we create good base for your project to grow.
Congrats for the new project!
Miguel

> From: [email protected]
> Date: Wed, 26 Aug 2015 16:37:22 +0000
> Subject: OT: how do you start designing a large project
> To: [email protected]
> 
> This is is out of topic but can someone please share personal
> experience/other resources about how do you start designing a new pretty
> large project? What I mean is that every web based application would have
> UI and a backend and they both non existent for the new project. Would you
> start designing your UI based on business requirements and then proceed to
> database already knowing what the UI needs  or would you start designing a
> solid database foundation first?
> 
> Thanks
                                          

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