On Tue, 9 Mar 2010, Curtis MacDuff wrote:

When this happens the mysqld service eats up loads of CPU and stops responding to requests from Amavisd-new.

Verify your schema, and that you're not missing any indexes.

And, as others have suggested, turn off auto-expiry and expire from a cron job scheduled at a time when your imbound email volume is low.

--
 John Hardin KA7OHZ                    http://www.impsec.org/~jhardin/
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