On Tuesday, July 4, 2017, 8:45:09 AM, Marc Perkel wrote:
[...]
> On Monday June 19 I got an infusion of ipilimumab which is an 
> immunotherapy drug. 2 days later I got a series of 3 radiation 
> treatments (21st thru 23rd). Dosage, 3 fractions of 9gy xrays from 
> Varian Trilogy set at 9MV. These treatment we unusual in that instead of
> irradiating the whole tumor, I asked that they just burn a disk in the
> center of the main tumor leaving the rest of the tumor undamaged. This
> request was very counter intuitive in radiology because they are trained
> to kill every cancer cell they can possibly hit and it took a lot of 
> work to get them to deliberately leave tumor undamaged.

> But that was important because I was turning the tumor into a school, 
> not a battlefield, where I was teaching my immune system what the cancer
> looked like (antigens) and classify it as an enemy. By using partial 
> radiation I created an environment where white blood cells in my immune
> system could interact with dead cancer and learn it.

> 4 days after treatment I started getting a reaction. I was queasy, low
> energy, aches and pains, chills. Wgen I got home I had a fever of 101,
> and it occurred to me, is this the fever I was hoping for?

> Fever indicates that I'm having an immune response. My immune system is
> fighting something. Was it attacking the cancer?
[..]

Hi Mark,
Thanks for the great news.  I truly hope it worked as planned.  If
this is something no one else has thought of before, then obviously
document it for science so it may save other people's lives.  :)

Cheers,

Jeff C.
-- 
Jeff Chan
mailto:je...@surbl.org
http://www.surbl.org/

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