How do you come up with Body Surface area? What would be considered average?

Mike Payne
On 02/01/2011, at 21:09 , Paul Trusten wrote:

> Dosing some medications in amount of drug per square meter of body surface 
> area *(BSA) instead of body mass takes into account the metabolic and drug 
> elimination differences among patients.   BSA dosing is often used for 
> anti-cancer (chemotherapy) drugs.
> ----- Original Message -----
> From: Bill Potts
> To: [email protected] ; 'U.S. Metric Association'
> Cc: [email protected] ; 'Gentry, Elizabeth'
> Sent: 02 January, 2011 11:34
> Subject: RE: [USMA:49395] powers of ten--becoming an exponent proponent
> 
> I agree with you, Paul. And, for the grade level at which exponents should be 
> taught, that seems about right.
>  
> The one thing that puzzles me is the milligrams per square meter dosage. I 
> can only think of this being used for some kind of skin cream, which leads to 
> the question of how one easily determines a patient's skin area. I have to 
> assume, though, that an approximation is probably close enough and that 
> order-of-magnitude errors are unlikely. :o)
>  
> Bill
> 
> From: [email protected] [mailto:[email protected]] On Behalf Of 
> Paul Trusten
> Sent: Sunday, January 02, 2011 08:40
> To: U.S. Metric Association
> Cc: [email protected]; [email protected]; Gentry, Elizabeth
> Subject: [USMA:49395] powers of ten--becoming an exponent proponent
> 
> The previous discussion of Zimbabwe currency in the article in question 
> (http://news.yahoo.com/s/ap/20110102/ap_on_re_af/af_zimbabwe_numbers_game )  
> reminded me that part of our problem in accepting metrication in the U.S. is 
> that we Americans are not yet proponents of exponents.  We tend to limit the 
> teaching  of exponents to a small part of our mathematics education and don't 
> apply that education to the practical subject of measurement.   When I stop 
> to consider the metric system, I sense that I am returning to eighth-grade 
> algebra, when I should have learned something about exponents much earlier 
> than that.  At least to me, facility in exponential notation makes the 
> meanings of the SI prefixes easier to understand and manipulate. 
>  
> I don't know what it's like in metric countries, but, here in the land of the 
> foot and the mile,  even the simplest application of exponents in connection 
> with SI falls on innumerate ears.  For example,  in pharmacy I have yet to 
> hear one of my colleagues look at the symbol m2 and pronounce it "square 
> meter."  They will pronounce it "meters squared," which may be good as an 
> exponential statement but, I think, bad as a measurement unit.  Some (usually 
> outside of pharmacy) can't even get that far, and will state a dose of 50 
> mg/m2 as "50 milligrams emm two,"  reading it out to me with difficulty, not 
> knowing what it means.  Pharmacists use common sense and can interpret, based 
> on the drug being ordered, that 50 milligrams per square meter is what was 
> meant, but if two people are communicating purely on the basis of the 
> expression being used, with nothing else to refer to, who knows? From the 
> resulting confusion,  we may get a medical Gimli Glider.
>  
> I remember, in the fourth grade (which, for me, was 50 years ago), learning 
> "decimal places,"  and learning the "millions place" and the "thousands 
> place," but at that time, those places were never connected to the concept of 
> bases and exponential notation.  Had that been done for us,I think we could 
> have adapted to the metric system the very next day and become metric 
> citizens.  
>  
> As I mentioned, I haven't been in the fourth grade for 50 years, and the 
> timing of the study of exponents may have changed since then (big grin).  I'd 
> be interested in what the teachers on this list think of the above. 
>  
> So, my question is:: to what extent do you think a thorough grounding in 
> exponential notation in the early years of mathematics education (2nd, 3rd 
> grade?)  would improve the ability of the U.S. to go metric?
>  
> Paul T.

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