John, the system problem is that teaspoonful is even allowed to be used in a 
prescription. As I mentioned, the Instiute of Safe Medication Practices 
(ISMP)---FINALLY, and in the year 2009!---recommended that household units be 
banned from the entire practice of healthcare (please see attached).  

 Yes, you're right, usually the mistake is in giving the volume to take, and 
yes, the pharmacist is the healthcare professional responsible for translating 
the dose into the correct volume for the caregiver to give the child.  I wish 
the article had said which drug product was in question, but as a pharmacist I 
will guess that it was loratadine oral solution (Claritin) 5 mg/5 mL, an 
antihistamine for the baby's irritated ear canal, so the dosage volume would be 
2 mL, and the dose placed on the label was 2 teaspoonfuls, or 10 mL.  The 
prescription was either illegible or it was dispensed hastily, i.e, without 
taking into account that it was a pediatric patient.  Still, there is no 
approved infant dose for Claritin, but 2 mg (2 mL) is a reasonable choice.  The 
error still hinges upon the habit of using teaspoonfuls, or 5 mL increments of 
volume. Even if the prescription was dispensed in haste (which is very, very 
likely today when a pharmacy is dispensing 400 to 600 prescriptions per day),  
the prescribing and dispensing habits for oral liquid medication in our country 
continue to emphasize the teaspoonful. Even doctors who come from other (i.e., 
metric) countries get into the bad habit of using teaspoonfuls when they study 
medicine in the U.S.  

If ISMP's recommendations had been followed (i.e., no use of the teaspoonful by 
the prescriber, the pharmacist, or the patient), then there would be no use of 
the teaspoonful at all, and the dose would have to have been translated into 
milliliters by the pharmacist.  Once again, there is also the possibility that 
the dose for a pediatric patient was not considered by the pharmacist who 
filled the prescription and, as too often happens, the prescription goes down 
the "assembly line" without being carefully checked.  But the magnitude of the 
overdose still hinges upon our insistence upon considering this primitive 5 mL 
unit we call one teaspoonful. The baby received a five-fold overdose.

ISMP has recommended the metrication oral liquid medication dosing in the U.S.  
It wasn't in place to protect this baby.

Paul

Paul Trusten, R.Ph. , Vice President
U.S. Metric Association, Inc.
www.metric.org
[email protected]
+1(432)528-8824
  ----- Original Message ----- 
  From: John M. Steele 
  To: U.S. Metric Association 
  Sent: 31 January, 2011 05:39
  Subject: [USMA:49711] Re: a non-metric U.S. can kill children


  Paul,
  I don't understand this from the article:
  "The boys father says he was diagnosed with an ear infection and given the 
wrong dosage by a 24-hour pharmacy, 2 teaspoons instead of 2 milligrams."



  If the dose printed was 2 tsp, it must have been a liquid medicine.  It may 
have been a reporter error ( 2 mL??), but the dose should have been a volume in 
milliliters.  If doctors, pharmacists, or vets (in the case of pet owners) 
believe the public can work concepts of weight based dosing or concentrations 
of liquid medicine, they are wrong.  I help out at a conversion site, and there 
is endless confusion over the concepts.  The doctor or pharmacist must reduce 
the dose to a patient-specific, volumetric dose for a liquid medicine; of 
course, they must work it correctly, too.




------------------------------------------------------------------------------
  From: Paul Trusten <[email protected]>
  To: U.S. Metric Association <[email protected]>
  Sent: Mon, January 31, 2011 4:03:55 AM
  Subject: [USMA:49710] a non-metric U.S. can kill children


  The President 
  The White House
  Washington, DC 29599
  2011-01-31

  Dear Mr. President,

  A few days ago, I wrote to you urging that the U.S. finally achieve its goal 
of changing over to the SI metric system of measurement for the economic and 
academic health of the nation.  Sometimes, however, our country needs to change 
over to metric for health reasons, period.  My subject line in this e-mail is 
no exaggeration.  American children are often harmed, or even killed, because 
our citizens, along with our healthcare professionals, drag traditional units 
of measurement (such as the teaspoonful) from the society at large into the 
hospital or clinic.  Too many times, we read of stories such as the one in the 
links below, where teaspoonsful and mililiters or milligrams get confused.  
Although the Institute for Safe Medication Practices reconnended  in 2009 that 
only metric units be used in connection with prescriptions, the following 
continues to take place, and will continue to take place until we as a people 
use only one system of measurement (metric):

  http://www.theredheadedpharmacist.com/?p=2956

  http://www.wrcbtv.com/Global/story.asp?S=13923416

  We need your leadership to help us "go metric" and save American lives.

  SIncerely,


  Paul Trusten, R.Ph. , Vice President and Public Relations Director
  U.S. Metric Association, Inc.
  www.metric.org
  [email protected]
  +1(432)528-8824





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