Go down to the Pharmacy and ask them for their copy of Trissels
handbook of injectable drugs. It is updated yearly and has the
info I just gave you on solubility. Every pharmacy has a copy
You will also find the info I gave you in Gahart Intravenous
Medications by Mosby which is also updated yearly
Hope that helps
kathy
________________________________
From: Heather Nichols [mailto:[EMAIL PROTECTED]
Sent: Mon 2/6/2006 8:13 AM
To: Kokotis, Kathy; [EMAIL PROTECTED]; [EMAIL PROTECTED];
[EMAIL PROTECTED]; Leigh Ann Bowe-geddes;
[EMAIL PROTECTED]
Subject: RE: Dilantin
Sounds like basic chemistry to me, but I to would like a reference
to show this, as I have been making an ongoing case against
Dilantin for some time now here at my facility.
Thanks Kathy
Heather Nichols RN BSN CRNI
Infusion Services
University of Louisville Trauma Institute
530 S. Jackson St.
Lou. Ky. 40202
(502)562-3530
"Lynn Hadaway" <[EMAIL PROTECTED]> 02/06/06 9:42 AM >>>
Kathy, I must ask for your reference for this information. Please
provide it or tell us where you are getting this concept. Thanks,
Lynn
At 7:09 PM -0700 2/5/06, Kokotis, Kathy wrote:
Dilantin is in some ways not even compatible with normal saline or
your bloodstream
Normal saline pH 5.5
Bloodstream pH 7.35
dilantin pH 12-14 but if it falls below 10 it precipitates. Both
blood and normal saline make the pH fall below 10 so therefore you
will find crystals of dilantin in the lungs if it does not
preceipitate sooner. Are we not lucky the lungs are a great filter
of life
Kathy
________________________________
From: [EMAIL PROTECTED] on behalf of Leigh Ann Bowe-
geddes
Sent: Sat 2/4/2006 6:34 AM
To: [EMAIL PROTECTED]; [EMAIL PROTECTED];
[EMAIL PROTECTED]
Subject: Re: Dilantin
Nancy:
Dilantin is very prone to precipitation. It is not compatible with
anything except NS. Flushing is very important, but there is another
issue. The lumen through which the dilantin is infused should be
dedicated to dilantin and NS only. Some of the drug may cling to the
internal lumen, and if anything other than NS is infused between
dilantin doses, you get dilantin crystals in the line.
There are some other issues with dilantin. It is very important to
flush well, and to administer the medication properly. It is not
stable if the pH is allowed to drop, and the normal pH of dilantin
is very high, somewhere in the 12-13 range.
Leigh Ann
Leigh Ann Bowe-Geddes, RN, CRNI
IV Therapy Specialist
Infusion Services Department
University of Louisville Hospital
Louisville, KY
502-562-3530
"Nancy Sullivan" <[EMAIL PROTECTED]> 02/03/06 8:26
PM >>>
I know you ladies and gentlmen have probably discussed this many
times, but I'm new to these message baords and have a questions.
My hospital has a policy that states: "DO NOT INFUSE DILANTIN THRU
PICC LINES." I have been working at this hospital for 3 years and it
>does seem like every time a nurse puts dilantin into a
picc--occlusion and loss of the line. I have been told that it is a
flushing problem and lack of education. We use groshong and per q
cath piccs. SO PLEASE EDUCATE ME IN THIS MATTER, BECAUSE I WOULD
LOVE TO EDUCATE THE REST OF THE STAFF.
Thanks in advance
Nancy Sullivan RN
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--
Lynn Hadaway, M.Ed., RNC, CRNI
Lynn Hadaway Associates, Inc.
126 Main Street, PO Box 10
Milner, GA 30257
http://www.hadawayassociates.com
office 770-358-7861
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