Central Line Infection

[Rakay Dance]

Hi,  I am looking for some expert opinions.  We had a PICC line in place 8 weeks.  Pt is receiving TPN for extreme hyperemesis gravadarium.  On weekly labs Monday the lab noted visiable bacteria in the CBC.  On Tuesday PICC was pulled and repeat CBC and Blood cultures PIV were drawn.  No bacteria noted on this sample.  Blood Cultures remain negative after 48 hours.  Is this likely a line infection or something else.  The tip was not cultured.  Pt is now hospitalized and continues to spike fevers and is on IVAB.  Infection remains unknown.  Pt’s WBC was 2.7 when admitted to hospital.  Pt has very large swollen glands in neck, headache and stiff neck.  No spinal has been done.  I would love your opinion’s—line infected or no??  RaKay