Theoretically this might be correct but not practical. When the occlusion is caused by something other than a blood clot inside the lumen or immediately at the catheter tip, you might not have a successful clearance procedure. You might be able to flush but still can not aspirate from the line. So in those cases the tpa will go into the bloodstream. But the dose is so low and the half life so short, the risk of bleeding is tremendously small. Lynn

At 1:13 PM -0700 9/28/06, Kelly Murphy wrote:
I don't know about our policies, but my question is in
addition to yours - if TPA is used to declot a line
properly, it should never enter the patient's
bloodstream, right?  So, there shouldn't be any
contraindications, right?  This isn't to argue, I
honestly want to know.
Thanks,
Kelly

--- Moore Beverly <[EMAIL PROTECTED]> wrote:

 TPA has the following contraindications:
 a.       Active internal bleeding
 b.      History of recent CVA (2 months or less)
 c.       Intracranial or or intraspinal bleeding
 d.      AV malformations or aneurysm
 e.       Recent (2 months or less) intracranial or
 intraspinal surgery
 f.        Uncontrolled hypertension
  Do you list any complications of Cathflo Activase
 in your policies?  I
 know the salesman says there are no
 contraindications,  Most of the
 doctors around here will not order if they are
 worried about bleeding.
 I don't have a package insert here at this time to
 read.



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--
Lynn Hadaway, M.Ed., RNC, CRNI
Lynn Hadaway Associates, Inc.
126 Main Street, PO Box 10
Milner, GA 30257
http://www.hadawayassociates.com
office 770-358-7861

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