On 22-dec-04, at 16:33, [EMAIL PROTECTED] wrote:
From your friendly teratologist...Per California's suggestion, the National (USA) MSDS for water also says that the LD50 (dosi lethalis fiv, or dose that kills 50% of all persons) is 12.2 liters per orum (by ingestion). I suppose if you don't drown first or die from your bladder exploding, this would be lethal! Does it mean that 12.1 liters is ok? ;)
Nope. Definition of LD50 (median lethal dose) is: that dose that will kill 50% of all test subjects within a set period of time (LD50 or LC50 values should always be accompanied by a time frame. Acute fish LC50s e.g. are for survival after 96 hours of continuous exposure). So at 12.1 liters you'd expect that less than 50% but significantly more than zero (unless the dose-response curve were ultrasteep) subjects would die. Plus you might still die after a longer observation period...
henk
==========================Heisenberg was right!======================== | Dr. Henk J.M. Verhaar | | | Environmental Fate and Ecotoxicology Specialist | | Fly Tier | web: www.xs4all.nl/~flyrod | | Stichts End 17 | e-mail: [EMAIL PROTECTED] | | NL-1244 PK Ankeveen | phone: +31 35 656 2128 | | the Netherlands | ICQ: 15727113 | ==========================Uncertainty happens!=========================
