I have I file that is something like:

ASN       144
ASN       144
HIS         145
HIS         145
LEU        146
LEU        146

Actually it has many more columns. I want to change that to:

ASN             1
ASN             1
HIS               2
HIS               2
LEU              3
LEU              3

That means, I want to subtract 143 from each value on the columns, and
write the result. Furthermore, the file contain other columns which I
don't want to modify. I have done scripts for that, but could that be
done with the substitute command of vim?

Thanks,
Leandro.


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