1 million? It would be out of reach of a person!

On 12/22/17, Dulce Muccio Weisenborn <[email protected]> wrote:
> NPR said perhaps one million for both eyes.
>
> -----Original Message-----
> From: [email protected] [mailto:[email protected]] On Behalf
> Of Mohib Anwar Rafay
> Sent: Friday, December 22, 2017 1:13 AM
> To: [email protected]
> Subject: Re: Attention to people with RP
>
> just wondering what will be the expensis incurred for this treatment?
>
> On 12/21/17, Marie <[email protected]> wrote:
>> I am including some information I received yesterday concerning a gene
>> therapy treatment which has been approved by the FDA for people with
>> Retinitis Pigmentosa. I am sending it to all the lists I currently belong
>> to
>> because it needs to get to as many RP sufferers as possible.
>> Marie
>> Foundation Fighting Blindness Celebrates Historic FDA Approval of
>>
>> First Gene Therapy to Treat Blindness
>>
>> Foundation’s early investment in LUXTURNA™ boosts vision-restoring
>> treatment
>> for people with RPE65 mutations and will help advance other gene
>> therapies
>> currently in development.
>>
>> (Columbia, MD) — Today’s U.S. Food and Drug Administration (FDA) approval
>> of
>> voretigene neparvovec, to be marketed as LUXTURNA, will be life-changing
>> for
>> patients with vision loss due to mutations in the RPE65 gene and a
>> watershed
>> moment for the inherited retinal disease field, says the Foundation
>> Fighting
>> Blindness. The Foundation was an important early investor in LUXTURNA,
>> providing $10 million in critical seed funding for the therapy.
>>
>> The groundbreaking treatment is the first gene therapy for the eye and
>> for
>> any inherited disease to be approved by the FDA. The treatment restores
>> vision by delivering working copies of the RPE65 gene directly into the
>> retina, thereby compensating for the nonfunctional, mutated genes.
>>
>> “We are thrilled for the patients whose lives will change dramatically
>> because of this treatment,” says David Brint, Foundation Fighting
>> Blindness
>> chairman. “We are also pleased to have this concrete example of the
>> strength
>> of the Foundation’s strategy of identifying and investing early in
>> promising
>> treatments. Doing so helps attract industry investment that can usher
>> promising treatments through clinical trials and ultimately FDA
>> approval.”
>>
>> LUXTURNA is the result of more than two decades of research and
>> development
>> at the University of Florida, the University of Pennsylvania, Children’s
>> Hospital of Philadelphia, and Spark Therapeutics. The Foundation Fighting
>> Blindness’ seed investment allowed researchers to take the therapy
>> through
>> the early investigational stages critical to any treatment development.
>>
>> “LUXTURNA will be life-changing for people with an inherited retinal
>> disease
>> caused by RPE65 mutations. For them, the treatment means alife of
>> independence. Also important is the momentum this approval provides to
>> other
>> gene-based therapies — for the eye and other diseases — now in the
>> clinic,”
>> says Benjamin Yerxa, PhD, Foundation CEO.
>>
>> An additional noteworthy milestone is the demonstrated value of a new
>> clinical endpoint devised by the Spark Therapeutics team to measure
>> LUXTURNA’s impact. The new measure, a multi-luminance mobility test
>> (informally called the maze), measured the impact of the treatment beyond
>> the traditional visual acuity measure — the eye chart. This new clinical
>> endpoint moves vision measures beyond the eye chart, which is
>> particularly
>> significant for people with low or no vision.
>>
>> Spark Therapeutics, which holds the biologics license for LUXTURNA and
>> conducted the clinical trials that showed its safety and efficacy, will
>> also
>> manage the treatment rollout. Spark has announced that in order to ensure
>> the treatment is safely administered, it will only be available through a
>> small number of centers of clinical excellence across the country. Spark
>> has
>> also expressed its commitment to educating third-party payers about the
>> value of LUXTURNA and to working to help ensure treatment access to all
>> eligible patients.
>>
>> Anyone in need of more information about LUXTURNA should contact Spark
>> Therapeutics at 1-833-SPARK-PS (833-772-7577). Another resource for
>> information is Spark’s website: www.Sparktx.com.
>>
>>
>> Foundation Fighting Blindness Celebrates Historic FDA Approval of
>>
>> First Gene Therapy to Treat Blindness
>>
>> Foundation’s early investment in LUXTURNA™ boosts vision-restoring
>> treatment
>> for people with RPE65 mutations and will help advance other gene
>> therapies
>> currently in development.
>>
>> (Columbia, MD) — Today’s U.S. Food and Drug Administration (FDA) approval
>> of
>> voretigene neparvovec, to be marketed as LUXTURNA, will be life-changing
>> for
>> patients with vision loss due to mutations in the RPE65 gene and a
>> watershed
>> moment for the inherited retinal disease field, says the Foundation
>> Fighting
>> Blindness. The Foundation was an important early investor in LUXTURNA,
>> providing $10 million in critical seed funding for the therapy.
>>
>> The groundbreaking treatment is the first gene therapy for the eye and
>> for
>> any inherited disease to be approved by the FDA. The treatment restores
>> vision by delivering working copies of the RPE65 gene directly into the
>> retina, thereby compensating for the nonfunctional, mutated genes.
>>
>> “We are thrilled for the patients whose lives will change dramatically
>> because of this treatment,” says David Brint, Foundation Fighting
>> Blindness
>> chairman. “We are also pleased to have this concrete example of the
>> strength
>> of the Foundation’s strategy of identifying and investing early in
>> promising
>> treatments. Doing so helps attract industry investment that can usher
>> promising treatments through clinical trials and ultimately FDA
>> approval.”
>>
>> LUXTURNA is the result of more than two decades of research and
>> development
>> at the University of Florida, the University of Pennsylvania, Children’s
>> Hospital of Philadelphia, and Spark Therapeutics. The Foundation Fighting
>> Blindness’ seed investment allowed researchers to take the therapy
>> through
>> the early investigational stages critical to any treatment development.
>>
>> “LUXTURNA will be life-changing for people with an inherited retinal
>> disease
>> caused by RPE65 mutations. For them, the treatment means alife of
>> independence. Also important is the momentum this approval provides to
>> other
>> gene-based therapies — for the eye and other diseases — now in the
>> clinic,”
>> says Benjamin Yerxa, PhD, Foundation CEO.
>>
>> An additional noteworthy milestone is the demonstrated value of a new
>> clinical endpoint devised by the Spark Therapeutics team to measure
>> LUXTURNA’s impact. The new measure, a multi-luminance mobility test
>> (informally called the maze), measured the impact of the treatment beyond
>> the traditional visual acuity measure — the eye chart. This new clinical
>> endpoint moves vision measures beyond the eye chart, which is
>> particularly
>> significant for people with low or no vision.
>>
>> Spark Therapeutics, which holds the biologics license for LUXTURNA and
>> conducted the clinical trials that showed its safety and efficacy, will
>> also
>> manage the treatment rollout. Spark has announced that in order to ensure
>> the treatment is safely administered, it will only be available through a
>> small number of centers of clinical excellence across the country. Spark
>> has
>> also expressed its commitment to educating third-party payers about the
>> value of LUXTURNA and to working to help ensure treatment access to all
>> eligible patients.
>>
>> Anyone in need of more information about LUXTURNA should contact Spark
>> Therapeutics at 1-833-SPARK-PS (833-772-7577). Another resource for
>> information is Spark’s website: www.Sparktx.com.
>>
>>
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>
>
> --
> Mohib Anwar Rafay
>
> Phone: +919 555 555 765
>
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> list.
>
> If you have any questions or concerns about the running of this list, or if
> you feel that a member's post is inappropriate, please contact the owners or
> moderators directly rather than posting on the list itself.
>
> Your V iPhone list moderator is Mark Taylor.  Mark can be reached at:
> [email protected].  Your list owner is Cara Quinn - you can reach Cara at
> [email protected]
>
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-- 
Mohib Anwar Rafay

Phone: +919 555 555 765

-- 
The following information is important for all members of the V iPhone list.

If you have any questions or concerns about the running of this list, or if you 
feel that a member's post is inappropriate, please contact the owners or 
moderators directly rather than posting on the list itself.

Your V iPhone list moderator is Mark Taylor.  Mark can be reached at:  
[email protected].  Your list owner is Cara Quinn - you can reach Cara at 
[email protected]

The archives for this list can be searched at:
http://www.mail-archive.com/[email protected]/
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