Hi Linfeng,
 the surface probably leads to degenerate Voronoi polygons somewhere in the 
smaller branches.
Try smoothing the surface first, using
vmtksurfacesmoothing -ifile airway.vtp -passband 0.01 -iterations 30 -ofile 
airway_smooth.vtp

maybe try with -passband 0.1 if the smoothing is too strong with 0.01.

I also suggest to get rid of the disconnected segments using 
vmtksurfaceconnectivity.

You can do everything in a single pipe

vmtksurfaceconnectivity -ifile airway.vtp --pipe vmtksurfacesmoothing -passband 
0.01 -iterations 30 --pipe vmtkcenterlines -ofile airway_centerlines.vtp

Let me know if this helps.


Luca


On Dec 22, 2011, at 4:29 PM, Lingfeng Zhuang wrote:

> Hi
> 
> I am trying to extract centerline for the polydata attached. But after
> picking start point and end points, the program did not return in two
> hours. Python took 100% CPU usage in this period.
> 
> The command used is vmtkcenterlines -ifile airway.vtp -ofile 
> foo_centerlines.vtp
> 
> Please help.
> 
> Best regards,
> 
> Jerry
> <airway.vtp><endpoints.JPG><startpoints.JPG>------------------------------------------------------------------------------
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Intel AppUpSM program developer opportunity. appdeveloper.intel.com/join
http://p.sf.net/sfu/intel-appdev
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