At 06:13 PM 7/18/2011, ecat builder wrote:
I created a simple wordpress blog where I will try to follow replicators. (<http://ecatbuilder.com>ecatbuilder.com) I will write about my research and say what works and what doesn't. Hope to hear from those with constructive ideas for experiments. If you know of professional or novice replicators, please let me know.

I'd like to know about them. For now, my suggestions:

Think small. Think many tests at once. Figure out the minimum size that might show some measurable effect, if you get anywhere in the vicinity of a working composition, and then design your apparatus to test many, many of these at once, as many as possible. You can then run large numbers of explorations. The calorimetry doesn't need to be stellar, indeed, you might just be looking for a relatively small temperature increase over control cells. You can test promising materials, later, in more accurate ways.

As I think of this, you have a thermocouple on each cell, you might have dozens or a hundred cells, even, with the data multiplexed. You'd load the cells with different materials, same mass in each cell, and the whole thing would be heated up to some operating temperature above the expected optiman level, with each cell's temperature being recorded during the heating, and during the cool-down. You would be looking for a bump. When you see one, if you see one, you'd then try a number of cells with those ingredients, looking for some reproducibility.

Then you'd vary the parameters for those ingredients, running a range of values in a combined run, looking, say, to plot temperature behavior versus, say, the concentration of an ingredient, trying to find an OOP, an optimum operating point.

Gradually, you will build up data on many different possible ingredients. Good luck finding any bumps.

There may be "false bumps," i.e., chemical effects. That's fine, you don't actually care -- not much, anyway. You'll sort this later. It is *comparative behavior* you are looking for. Once you find the best you can find, then you'd want to look to see if this is chemistry.

That's my idea, any way.

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