2013/9/3 Chandan Choudhury <[email protected]>:
> Thanks Christoph,
>
> Indeed the csg_stat and  csg_boltzmann gives same distribution. I far as I
> understand VOTCA, this is always true. So, how does one take care this type
> of scenario where one has faint minima in the normalized plot. I can always
> take the un-normalized plot as the guess potential. Would this be the right
> approach?
I not sure here, I leave this question to the bio-guys on this list.

>
> Any insight would be very helpful.
>
> Chandan
>
>
> --
> Chandan kumar Choudhury
> NCL, Pune
> INDIA
>
>
> On Fri, Aug 30, 2013 at 10:08 AM, Chandan Choudhury <[email protected]>
> wrote:
>>
>>
>>
>> On Thu, Aug 29, 2013 at 10:42 PM, Christoph Junghans <[email protected]>
>> wrote:
>>>
>>> 2013/8/29 Chandan Choudhury <[email protected]>:
>>> >
>>> > On Thu, Aug 29, 2013 at 10:14 PM, Christoph Junghans
>>> > <[email protected]>
>>> > wrote:
>>> >>
>>> >> 2013/8/29 Chandan Choudhury <[email protected]>:
>>> >> > Dear votca users,
>>> >> >
>>> >> > I have an angle distribution of beads, such that it peaks ~2.85 rad
>>> >> > (163
>>> >> > deg, xvg, file (ABC.angle) is attached). Now if I do Boltzmann
>>> >> > inversion
>>> >> > on
>>> >> > it (with normalization 1/sin), it produces a very faint hump,
>>> >> > actually
>>> >> > no
>>> >> > minima exists, around 2.8 rad (Fig ABC.angle.pot attached). In this
>>> >> > case,
>>> >> > how would the beads sample the region. Or how would votca take care.
>>> >> How did you arrive at ABC.angle.pot? Is ABC.angle already normalized
>>> >> with
>>> >> /1sin?
>>> >> If I plot log(ABC.angle) it has a minimum!
>>> >>
>>> >
>>> > ABC.angle.pot is the outcome of csg_boltzmann. It is not normalized
>>> > with
>>> > 1/sin. Without the normalization it does has the minimum.
>>> Have you checked that you get the same with csg_stat?
>>
>>
>> Yes. csg_stat and csg_boltzmann gives the overlapping distributions.
>>>
>>> >
>>> >>
>>> >> >
>>> >> > Also, can someone help me to understand the origin of normalisation
>>> >> > by
>>> >> > 1/r^2
>>> >> > and 1/sin for bonds and angle, respectively.
>>> >> 1/sin and 1/r^2 are just volume elements, which are needed as bigger r
>>> >> (angles around pi/2) are more likely to happen due to volume variable
>>> >> space.
>>> >
>>> > Thanks for the explanation,
>>> >>
>>> >>
>>> >> Have a look at this paper and its supporting information for some
>>> >> examples of angle potentials:
>>> >> "Multiscale simulation of small peptides: Consistent conformational
>>> >> sampling in atomistic and coarse-grained models"
>>> >> Olga Bezkorovaynaya, Alexander Lukyanov, Kurt Kremer, Christine Peter
>>> >
>>> >
>>> > I will surely have a look at this.
>>> >
>>> > Thanks
>>> >>
>>> >>
>>> >>
>>> >>
>>> >> >
>>> >> > Thanks
>>> >> >
>>> >> > Chandan
>>> >> >
>>> >> > --
>>> >> > Chandan kumar Choudhury
>>> >> > NCL, Pune
>>> >> > INDIA
>>> >> >
>>> >> > --
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>>> >>
>>> >>
>>> >>
>>> >> --
>>> >> Christoph Junghans
>>> >> Web: http://www.compphys.de
>>> >>
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>>>
>>> --
>>> Christoph Junghans
>>> Web: http://www.compphys.de
>>>
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>>
>>
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-- 
Christoph Junghans
Web: http://www.compphys.de

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