Hi Guo,

Instead of NVT you may proceed with NPT with plucking off the constraints.
Once your system is equilibrated, then you may proceed for NVT.

Chandan


--
Chandan kumar Choudhury
NCL, Pune
INDIA


On Tue, Oct 15, 2013 at 9:06 AM, 郭志成 <[email protected]> wrote:

> Hi
>
>
> When I am running the NVT simulation, I get the LINCS warning message in the 
> enclosure file (nohup.out). We use the Amorphous cell tools in Materials 
> Studio to build the simulation box containing 856 molecules with the density 
> of 1.8g/cm
> 3
> (box length=5.597nm).What's the problem about my simulation? Whether the 
> simulation box is too small? How can I fix it? Thanks for anyone's help.
>
> Best regards!
>
> Zhicheng Guo
>
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