Hi Sikandar

 Thank you by your answer and explanation, I will check RDF convergence.
 I found that convergence is mostly like a damped oscillator not directly
converging to less error each time.
 Thank you , have a nice weekend
 Regards,
 Marc



On Sat, May 3, 2014 at 1:29 PM, Sikandar Mashayak <[email protected]>wrote:

> Hi Marc
>
> Did you check the CG-CG RDF at 300the step? How do they compare with the
> reference RDF?
>
> In my experience, I found that, in the case of bulk water, with the
> current RE minimization method in VOTCA,
> the CG potentials more or less converge to the values which reproduce
> target RDF in less than 200 iterations.
> However, due to statistical nature of short CG-MD simulations at every
> update step, the values of CG potentials
> fluctuate around the converged values. These fluctuations may or may not
> satisfy the convergence check criteria, i.e., they may be smaller or larger
> than the specified tolerance, and it depends on various setting parameters
> such as length of CG-MD simulations, relaxation parameters, and number of
> knot values.
>
> Therefore, it is always good to check the CG particle RDFs periodically to
> judge whether the RE minimization is
> converged or not. I guess, in VOTCA, there is a way to use CG particle
> RDFs as a measure to decide convergence. I will check how to do that and
> get back to you.
>
> We are also working on implementing alternative approach for RE
> minimization, which is a deterministic approach. It is based on reweighting
> strategy. You can read more about it in the article
>
> Chaimovich, Aviel, and M. Scott Shell. “Coarse-Graining Errors and
> Numerical Optimization Using a Relative Entropy Framework.” *The Journal
> of Chemical Physics* 134, no. 9 (March 3, 2011): 094112.
> doi:10.1063/1.3557038
>
> I hope it helps. Let us know if you have any further questions or
> suggestions.
>
> Thanks,
> Sikandar
>
>
>
>
>
>
> On Fri, May 2, 2014 at 4:31 PM, Marc Segovia <[email protected]>wrote:
>
>> Hi
>>
>> Last days I run relative entropy tutorial, using votca 1.3, in spce water
>> model
>> After several days in my PC, finally the cg don't converge.
>>
>> step 300 done, needed 1083 secs
>> Doing convergence check: default
>> Iterations are not converged, going on
>>
>> My question is , this happens because a convergence of 0.001 is to small,
>> or because numerical errors in my software or because the number of
>> configuration to average is too low , 50 ? or something else.
>>
>> Thanking in advance by your help
>>
>> Best Regards
>>
>> Marc
>>
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