2016-02-24 19:45 GMT-07:00 Alireza Moradzadeh <[email protected]>:
> Dear All,
>
> I am working with GROMACS to obtain potential between beads of two
> molecules.
> Molecule 1 has three beads with partial charges on each bead.
> Molecule 2 has only one bead with opposite charge equal to summation of
> charge of molecule 1.
>
> When I use energy groups for gormacs with PME my system blows up unless I
> put charges equal to zero on all of beads.
> My system works well when I use LJ parameters with PME and LINCS algorithm
> I did not find any coarse graining sample for charged molecules. How can I
> use table with partial charges on each bead.
It seems to me, there is a problem in your setup.

You could try to use the default 12-6 LJ table with your LJ parameters
to check if the problem comes from switching to tabulated interactions
itself or if it is due to your special table.
The default 6-12 table is in /usr/share/gromacs/top/table6-12.xvg. And
please note for tables it is easier to use C6/C12 combination rules
instead of sigma/eps, which means using combination rule 1 in the [
defaults ] block.

VOTCA only uses the C12 (6th & 7th) columns for iterating interactions
and hence it doesn't matter (in an IBI setup) what value C6 has and
C12 just act as a global scaling parameter, which we usually set to 1.
So in some sense VOTCA's table are simpler
column 1: r
column 2-5: doesn't matter, so put 0
column 6+7; potential + derivative
To  convert table6-12.xvg to a VOTCA style table column 6 would
C6*(column 4) + C12*column 6 of table6-12.xvg.

The main reason why VOTCA uses the C12 columns instead of the C6
columns is historically, but one doesn't need both as for
coarse-grained interactions the distinction between C6 and C12 makes
not much sense.

Christoph
>
> Should I use lammps instead of GROMACS.
>
> Thanks
>
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-- 
Christoph Junghans
Web: http://www.compphys.de

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