Wow, nobody can answer this straightaway? - I wonder: does this mean that 
no non-associate of the VOTCA team ever used RE method for their actual 
problem (i.e. not a tutorial case)?

Anyway, may I ask those on the team now: in what relation VOTCA's B-spline 
definition is with the corresponding Sci-Py class 
(scipy.interpolate.BSpline)?

https://docs.scipy.org/doc/scipy/reference/generated/scipy.interpolate.BSpline.html

I also have another question: what is the actual format of the .param.init 
file? - it is far from being clear in the manual, as the file itself is 
never described.

Thanks again.

Andrey

On Wednesday, July 18, 2018 at 6:51:44 PM UTC+1, Andrey Brukhno wrote:
>
> Hello,
>
> In an attempt to compare some data obtained with IBI to RE, I am trying to 
> start a relative entropy iteration for the same system. However, I do not 
> know how to generate the initial parameters (aka CG-CG.param.init file) for 
> my system (which would comprise 10 different interaction types).
>
> Initially I thought VOTCA would be able to generate the necessary 
> *.param.init files based on my initial potentials provided as *.pot.in 
> (the IBI results) and/or distributions (*.dist.tgt). But it seems not to be 
> the case, as it complaints in the inverse.log about missing *.param.init 
> files.
>
> Can anyone suggest a workaround? - I googled and searched here but did not 
> find anything regrading a practical way of creating those files (nor in the 
> manual).
>
> Please note: my question is very practical - I know how fit numerical data 
> with regular cubic splines, say in Grace, but VOTCA is using B-splines 
> which are more general (which is good!) but also more involved, so I guess 
> the coefficients of cubic splines cannot be used as initial "guess" for the 
> RE iteration. 
>
> I essentially need to know what software could do that - ?
>
> Thanks in advance!
>
> Andrey
>

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