On Mon, Jul 23, 2018 at 7:02 AM, 'Andrey Brukhno' via votca
<[email protected]> wrote:
>
> On Mon, Jul 23, 2018 at 1:46 PM, Christoph Junghans <[email protected]>
> wrote:
>>
>> On Mon, Jul 23, 2018 at 6:39 AM, 'Andrey Brukhno' via votca
>> <[email protected]> wrote:
>> > On Mon, Jul 23, 2018 at 1:17 PM, Christoph Junghans <[email protected]>
>> > wrote:
>> >>
>> >> On Mon, Jul 23, 2018 at 2:39 AM, 'Andrey Brukhno' via votca
>> >> <[email protected]> wrote:
>> >> >
>> >> > On Mon, Jul 23, 2018 at 2:22 AM, Christoph Junghans
>> >> > <[email protected]>
>> >> > wrote:
>> >> >>
>> >> >> On Sun, Jul 22, 2018 at 1:27 PM, 'Andrey Brukhno' via votca
>> >> >> <[email protected]> wrote:
>> >> >> > Thanks for your reply Christoph.
>> >> >> >
>> >> >> > I did check it, but inverse.log does not contain sufficient info,
>> >> >> > see
>> >> >> > the
>> >> >> > extract below.
>> >> >> > I will be investigating it further to make sure I did not do
>> >> >> > anything
>> >> >> > stupid
>> >> >> > myself, although I haven't changed much for the test iteration
>> >> >> > except
>> >> >> > recompiling the tpr files for the newer version of Gromacs).
>> >> >> The " rdf calculation is already done" tells me that this is not a
>> >> >> run
>> >> >> from scratch.
>> >> >> Try a fresh run, because some chance in the xml don't get populated
>> >> >> until the next iteration step.
>> >> >>  And grep for "csg_stat" (not rdf), you should see actually command,
>> >> >> which got run, e.g.:
>> >> >> "Running critical command 'csg_stat --nt 4 --options settings.xml
>> >> >> --top topol.tpr --trj traj.xtc --begin 20 --first-frame 0' "
>> >> >> From that you can see if all the options are read as excepted.
>> >> >>
>> >> >
>> >> > I knew you were going to say this...
>> >> > As a matter of fact, there is no such message from
>> >> > calc_rdf_generic.sh,
>> >> > but
>> >> > instead:
>> >> >
>> >> >   msg "Calculating rdfs with csg_stat using $tasks tasks"
>> >> >   critical csg_stat --nt $tasks --options "$CSGXMLFILE" --top
>> >> > "$topol"
>> >> > --trj
>> >> > "$traj" --begin $equi_time --first-frame $first_frame ${error_opts}
>> >> > ${maps:+--cg ${maps}}
>> >> >   mark_done "rdf_calculation${suffix}"
>> >> Well the "critical" function includes the print statement:
>> >> critical() {
>> >>   [[ $quiet = "no" ]] && echo "Running critical command '$*'" >&2
>> >>    "$@" || die "${FUNCNAME[0]}: '$*' failed"
>> >> }
>> >> So I am not sure when that got lost in your case.
>> >> >
>> >> > so I had to add this after the msg and before the csg_stat call:
>> >> >   echo "Doing: critical csg_stat --nt $tasks --options "$CSGXMLFILE"
>> >> > --top
>> >> > "$topol" --trj "$traj" --begin $equi_time --first-frame $first_frame
>> >> > ${error_opts} ${maps:+--cg ${maps}}"
>> >> >
>> >> > This shows me that topol-rdf.tpr is actually used (extract from
>> >> > inverse.log):
>> >> >
>> >> > Make update for ibi
>> >> > Calculating rdfs with csg_stat using 4 tasks
>> >> > Doing: critical csg_stat --nt 4 --options
>> >> >
>> >> >
>> >> > /home/andrey/Work/Models/DOPC-long-wtip4p-new/ibi-Rc1.65nm-freeN-dihs_CG-fits1-151cT/dopc_cg-int-map11.xml
>> >> > --top topol-rdf.tpr --trj traj.xtc --begin 0 --first-frame 0
>> >> > --block-length
>> >> > 1000000 --ext dist.block --cg
>> >> >
>> >> >
>> >> > /home/andrey/Work/Models/DOPC-long-wtip4p-new/ibi-Rc1.65nm-freeN-dihs_CG-fits1-151cT/dopc_cg-map11.xml;
>> >> > begin to calculate distribution functions
>> >> >
>> >> > However, the distributions are still wrong, and I am lost now as to
>> >> > which
>> >> > program to blame (again all the initial files are the same as in my
>> >> > previous
>> >> > iteration).
>> >> > I compared the outputs of `gmx dump topol-rdf.tpr' and `gmx dump
>> >> > topol.tpr'
>> >> > generated with the new Gromacs and everything seems alright, the
>> >> > relevant
>> >> > differences in exclusion lists are there.
>> >> > The problem is also that the original calculation was done on a
>> >> > cluster
>> >> > more
>> >> > than a year ago, so I cannot reproduce exactly all the installation
>> >> > setup,
>> >> > not on my desktop anyway. But I know that those calculations were
>> >> > correct
>> >> > and well converged.
>> >> >
>> >> > So something should have changed somewhere within the newly installed
>> >> > Gromacs/VOTCA combination.
>> >> You can see what VOTCA has with:
>> >> csg_dump --top topol-rdf.tpr --cg dopc_cg-map11.xml
>> >
>> >
>> > OK, but its output does not contain any info about the exclusions.
>> >
>> >>
>> >>
>> >> Remember, if you are using a mapping file ("--cg" option) exclusions
>> >> from the topology file are ignored and the ones from the mapping file
>> >> are used instead.
>> >
>> >
>> > Alright, this must be the root of my problem!
>> > Apparently, in v1.3 csg_stat would take the exclusions from tpr, not
>> > xml,
>> > because I never provided any exclusion list in any xml file, but it did
>> > work
>> > correctly!
>> This behavior hasn't changed for long time and was certainly the same
>> in v1.3 as well.
>
>
> I am only reporting my experience: version 1.3 (installed on our cluster 8
> Feb 2015) did not need any extra exclusion definitions (nrex) nor list and I
> had no problem obtaining correct distributions with topol-rdf.tpr only (the
> number provided by [moleculetype] is 10).
> But now, as of v1.41, the distributions correspond to exclusions starting
> with 1-4 intra-molecular pairs (the number provided by [moleculetype] is 3).
>
> Since I did not have any issue before, I did not care about generating
> exclusion lists in addition to tpr files.
Well then don't specify a mapping or a secondary tpr file. Both
together don't make much sense.

>
>>
>> When using a mapping file, exclusions get generated for each bond,
>> angle and dihedral interaction in the mapping file.
>>
>> Why are using a mapping file to begin with?
>
>
> Good question!
> Well, the manual advises to use cg.inverse.map tag with a one-to-one mapping
> xml file for iterative methods even when optimising only non-bonded
> interactions (and I recall having problems without this tag!), so I have:
I guess you are referring to section 7.3.2, but that is referring to
IMC (not IBI).
And even then, that has already been improved a while (pre-v1.3) ago,
so that section should probably get removed unless you remember a
reason why it is needed for IMC.

>
>      <map>
>       <DESC>Special mapping file for rdf calculations needed for bonded
> interactions</DESC>
>       dopc_cg-map11.xml
>     </map>
>
> and of course I do not do anything special about the csg_stat call in
> calc_rdf_generic.sh, so it does what it does.
>
> Andrey
>
>>
>> Christoph
>> >
>> > I will look into this again.
>> >
>> > Andrey
>> >
>> >>
>> >>
>> >> Christoph
>> >> >
>> >> > Andrey
>> >> >
>> >> >> Christoph
>> >> >> >
>> >> >> > Andrey
>> >> >> > -----
>> >> >> > $ grep rdf inverse.log
>> >> >> > ...
>> >> >> > cp_from_main_dir: 'grompp.mdp* topol.top* topol-rdf.tpr
>> >> >> > table_??.xvg
>> >> >> > index.ndx* conf.gro*'
>> >> >> > cp_from_main_dir: 'grompp.mdp* topol.top* topol-rdf.tpr
>> >> >> > table_??.xvg
>> >> >> > index.ndx* conf.gro*'
>> >> >> > cp_from_main_dir: 'grompp.mdp* topol.top* topol-rdf.tpr
>> >> >> > table_??.xvg
>> >> >> > index.ndx* conf.gro*'
>> >> >> > cp_from_main_dir: 'grompp.mdp* topol.top* topol-rdf.tpr
>> >> >> > table_??.xvg
>> >> >> > index.ndx* conf.gro*'
>> >> >> > cp_from_main_dir: 'grompp.mdp* topol.top* topol-rdf.tpr
>> >> >> > table_??.xvg
>> >> >> > index.ndx* conf.gro*'
>> >> >> > ‘sim_0/topol-rdf.tpr’ -> ‘./topol-rdf.tpr’
>> >> >> > Calculating rdfs with csg_stat using 4 tasks
>> >> >> > Calculating average rdfs and its errors for interaction TCH-TCH
>> >> >> > rdf calculation is already done
>> >> >> > Calculating average rdfs and its errors for interaction TCH-TCO
>> >> >> > rdf calculation is already done
>> >> >> > Calculating average rdfs and its errors for interaction TCO-TCO
>> >> >> > rdf calculation is already done
>> >> >> > Calculating average rdfs and its errors for interaction TCH-PO
>> >> >> > rdf calculation is already done
>> >> >> > Calculating average rdfs and its errors for interaction TCH-NH
>> >> >> > rdf calculation is already done
>> >> >> > Calculating average rdfs and its errors for interaction TCO-PO
>> >> >> > rdf calculation is already done
>> >> >> > Calculating average rdfs and its errors for interaction TCO-NH
>> >> >> > rdf calculation is already done
>> >> >> > Calculating average rdfs and its errors for interaction PO-PO
>> >> >> > rdf calculation is already done
>> >> >> > Calculating average rdfs and its errors for interaction PO-NH
>> >> >> > rdf calculation is already done
>> >> >> > Calculating average rdfs and its errors for interaction NH-NH
>> >> >> >
>> >> >> >
>> >> >> >
>> >> >> > On Sun, Jul 22, 2018 at 1:26 PM, Christoph Junghans
>> >> >> > <[email protected]>
>> >> >> > wrote:
>> >> >> >>
>> >> >> >> On Sat, Jul 21, 2018 at 9:01 PM, 'Andrey Brukhno' via votca
>> >> >> >> <[email protected]> wrote:
>> >> >> >> > Hello,
>> >> >> >> >
>> >> >> >> > I encountered a very strange (looks like legacy) issue with
>> >> >> >> > v1.4.1.
>> >> >> >> > In my earlier IBI iterations (with v1.3) I normally used
>> >> >> >> > special
>> >> >> >> > topol-rdf.tpr which was different from normal CG simulation
>> >> >> >> > topol.tpr
>> >> >> >> > by
>> >> >> >> > not
>> >> >> >> > including the intra-molecular pairs in the RDF stats (done by
>> >> >> >> > csg_stat).
>> >> >> >> > I
>> >> >> >> > wanted to make sure my previous results are reproduced by
>> >> >> >> > v1.4.1,
>> >> >> >> > so
>> >> >> >> > copied
>> >> >> >> > all the initialisation files into a new directory and tried to
>> >> >> >> > run
>> >> >> >> > once
>> >> >> >> > again. After the very first iteration I checked the obtained
>> >> >> >> > RDFs
>> >> >> >> > and
>> >> >> >> > they
>> >> >> >> > were all wrong - corresponding to normal topol.tpr (including
>> >> >> >> > intra-pairs)
>> >> >> >> > and not topol-rdf.tpr (excluding intra-pairs)!
>> >> >> >> >
>> >> >> >> > I guess there might have been changes made to locations or
>> >> >> >> > names
>> >> >> >> > of
>> >> >> >> > tags
>> >> >> >> > in
>> >> >> >> > settings.xml between the VOTCA versions, but I could not
>> >> >> >> > identify
>> >> >> >> > those
>> >> >> >> > changes by referring to the most recent manual (both v1.4.1 and
>> >> >> >> > development
>> >> >> >> > versions).
>> >> >> >> >
>> >> >> >> > Below is the relevant extract from my settings.xml file.
>> >> >> >> >
>> >> >> >> > Any clue, hint, advice are most welcome!
>> >> >> >> We haven't changes any tags in IBI since v1.4.1 and the special
>> >> >> >> topology for IBI can be set by cg.inverse.<sim_prog>.rdf.topol,
>> >> >> >> which
>> >> >> >> you did below.
>> >> >> >> You could try "grep csg_stat inverse.log" to figure out if the
>> >> >> >> right
>> >> >> >> topology got appended to the command line of csg_stat.
>> >> >> >>
>> >> >> >> Christoph
>> >> >> >> >
>> >> >> >> > Thanks in advance.
>> >> >> >> > Andrey
>> >> >> >> >
>> >> >> >> > -----------
>> >> >> >> >     <gromacs>
>> >> >> >> >       <grompp>
>> >> >> >> >         <bin>gmx grompp</bin>
>> >> >> >> >         <!--opts></opts-->
>> >> >> >> >       </grompp>
>> >> >> >> >       <mdrun>
>> >> >> >> >         <!--command>grmx-vtc-rerun.sh</command-->
>> >> >> >> >         <!--command>mpirun -lsf mdrun_mpi</command-->
>> >> >> >> >         <!--opts>-multidir sim_0 sim_1 sim_2 sim_3</opts-->
>> >> >> >> >         <command>mpirun -n 4 mdrun_mpi</command>
>> >> >> >> >         <opts>-multidir sim_0 sim_1 sim_2 sim_3 -tablep
>> >> >> >> > table.xvg
>> >> >> >> > -tableb
>> >> >> >> > table_b?.xvg table_a?.xvg table_d?.xvg</opts>
>> >> >> >> >       </mdrun>
>> >> >> >> >       <!--mdrun><opts>-nt 2</opts></mdrun-->
>> >> >> >> >       <!-- trash so many frames at the beginning -->
>> >> >> >> >       <equi_time>0</equi_time>
>> >> >> >> >       <!-- grid for table*.xvg !-->
>> >> >> >> >       <table_bins>0.001</table_bins>
>> >> >> >> >       <!-- cut the potential at this value (gromacs bug) -->
>> >> >> >> >       <pot_max>10000</pot_max>
>> >> >> >> >       <!-- extend the tables to this value -->
>> >> >> >> >       <table_end>2.5</table_end>
>> >> >> >> >       <initial_configuration>maindir</initial_configuration>
>> >> >> >> >       <rdf>
>> >> >> >> >         <block_length><DESC>Length of the block for the error
>> >> >> >> > analysis</DESC>
>> >> >> >> >           1000000
>> >> >> >> >         </block_length>
>> >> >> >> >         <map><DESC>Special mapping file for rdf calculations
>> >> >> >> > needed
>> >> >> >> > for
>> >> >> >> > bonded interactions</DESC>
>> >> >> >> >           dopc_cg-map11.xml
>> >> >> >> >         </map>
>> >> >> >> >         <topol><DESC> Gromacs binary topol (tpr) file to be
>> >> >> >> > used
>> >> >> >> > for
>> >> >> >> > csg_stat</DESC>
>> >> >> >> >           topol-rdf.tpr
>> >> >> >> >         </topol>
>> >> >> >> >         <with_errors>yes<DESC>calculate error on the rdf:
>> >> >> >> > yes/no</DESC>
>> >> >> >> >         </with_errors>
>> >> >> >> >       </rdf>
>> >> >> >> >     </gromacs>
>> >> >> >> > -----------
>> >> >> >> >
>> >> >> >> > --
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>> >> >> >>
>> >> >> >>
>> >> >> >>
>> >> >> >> --
>> >> >> >> Christoph Junghans
>> >> >> >> Web: http://www.compphys.de
>> >> >> >>
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>> >> >> Christoph Junghans
>> >> >> Web: http://www.compphys.de
>> >> >>
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>> >> Christoph Junghans
>> >> Web: http://www.compphys.de
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