Hi Christoph & Sikandar,

It's been a while since I asked the question below...

On Monday, July 23, 2018 at 7:51:14 PM UTC+1, Andrey Brukhno wrote:
>
>
> >>> Actually, I am a bit confused not seeing re.traj tag for atomistic
>> >>> trajectory. I thought RE iteration requires recalculating CG averages 
>> in
>> >>> over atomistic ensemble (trajectory) for every new set of CG 
>> potentials?
>> >>>
>> >>> Also, what about the corresponding re.topology tag - specifying what?
>> >>
>> >> Both options exist:
>> >>
>> >> 
>> https://github.com/votca/csg/blob/master/share/scripts/inverse/update_re.sh#L30
>> >>
>> >
>> > Just to clarify: above you confirm that the two tags
>> > `cg.inverse.$sim_prog.re.topol' and `cg.inverse.$sim_prog.re.traj' 
>> specify
>> > the tpr and xtc/trr files for the original fine-detail (atomistic)
>> > simulation?
>> No these are just options, which allow you to overwrite the
>> coarse-grained topology and trajectory.
>> Nothing atomistic here!
>
>
 

> If so, I am back to my question of how are the averages over fine detail 
> (atomistic) ensemble calculated for a new CG model/FF at each iteration?
> I am referring to Eqs. 2.24 and 2.26 in the manual (page 8).
>

According to the equations each RE iteration should recalculate the 
averages corresponding to the "AA" (fine-detail) ensemble using a new CG 
representation (i.e. updated force-field), and this is what I fail to find 
in the tutorial for spce/re. 

Could you please clarify this.

Andrey

 

>  
>
>>
>> > For reference, below is the extract from 
>> `share/votca/xml/csg_defaults.xml',
>> > where no traj tag is present (this is for v1.4.1, so perhaps in v1.5.1 
>> the
>> > tag is there?):
>> >
>> >       <re>
>> >               <topol>
>> >                 <DESC>Special topology file to be used for
>> > csg_reupdate</DESC>
>> >               </topol>
>> >       </re>
>> >
>> > Btw, my original question was: why these are not specified in 
>> `settings.xml'
>> > in the (spce/re) case you referred to above?
>> If they are not specified the default topology (topol.tpr) and default
>> trajectory (traj.xtc) are used.
>>
>> >
>> > Thanks / Andrey
>> >
>> >> Christoph
>> >>
>> >>>
>> >>> Andrey
>> >>>
>> >>>>
>> >>>>
>> >>> --
>>
>

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