On Thu, Jan 16, 2020 at 8:38 AM CHRISTINA-ANNA GATSIOU <
[email protected]> wrote:

> Hi Christoph,
>
> I managed to resolve the issue with non-bonded interactions by not using
> the toopology.xml when fitting the non-bonded interactions and by using
> nrexcl is 3 in topol.top.
> However it does not make sense why it did not work before since bonds etc
> were appropriately specified.
>
I looked at topology_.xml brief and it is really long, so I have two
guesses:
- you simply forgot to list a bond
- nrexcl corresponds to 3 bond length exclusions, .i.e. in a bond A-B-C-D,
A and D are excluded, even though there is no bond between A and D, so you
would need to add a non-physical bond to your topology_.xml

> There is one additional problem with the convergence of angles and
> dihedrals. Having fixed the nonbonded interactions, the angle distributions
> do not seem to improve.
>
 dihedrals have long convergence in general, but angles could be slow as
well depending on your system. Did you look at the angle auto-correlation
time to get a feel if the distribution are sampled went enough?

Christoph

>
> Best regards,
> Christianna
>
> On Wednesday, January 8, 2020 at 3:10:37 PM UTC+2, Christoph Junghans
> wrote:
>>
>>
>>
>> On Wed, Jan 8, 2020 at 02:56 CHRISTINA-ANNA GATSIOU <
>> [email protected]> wrote:
>>
>>> Hi Christoph,
>>>
>>> "Ok, if you are using a mapping file (--cg option), the exclusion from
>>> the tpr get mapped out."
>>> Does this mean that I should not be using the mapping file in order for
>>> the exclusions to be taken into account. I was under the impression that it
>>> was necessary. I have already defined those bonds in the mapping file.
>>>
>> It depends, a mapping file is usually only needed if you want to do IBI
>> on the bonded interactions as well.
>>
>> As VOTCA has no concept of nrexcl in gromacs once you map, you might need
>> to more unphysical bonds, e.g. using a tpr with a chain with bonds A-B-C, A
>> & C would be excluded if nrexcl is 2, after mapping A & B as well as B & C
>> are excluded, but A & C are not, so you will need to add an unphysical bond
>> between A & C to achieve that. Looking at the output of “csg_dump —excl
>> —top topol” vs. “csg_dump —excl —top topol.tpr —cg map.xml” should reveal
>> that.
>>
>> Can you send your tpr and mapping files?
>>
>>>
>>>
>>>
>>> On Monday, January 6, 2020 at 8:34:01 PM UTC+2, Christoph Junghans wrote:
>>>
>>>> On Mon, Jan 6, 2020 at 10:26 AM CHRISTINA-ANNA GATSIOU
>>>> <[email protected]> wrote:
>>>> >
>>>> >
>>>> >
>>>> > On Friday, January 3, 2020 at 5:30:28 PM UTC+2, Christoph Junghans
>>>> wrote:
>>>> >>
>>>> >>
>>>> >>
>>>> >> On Fri, Jan 3, 2020 at 8:13 AM CHRISTINA-ANNA GATSIOU <
>>>> [email protected]> wrote:
>>>> >>>
>>>> >>> Hi Christoph,
>>>> >>>
>>>> >>> I have set all exclusions in the gromacs topology file. However,
>>>> during IBI for one nonbonded interaction I get the attached distribution
>>>> (red corresponds to the bond distribution the bonded beads, green
>>>> corresponds to the target distribution of bead types and blue to IBI
>>>> distribution at step 30). It seems that bonded pairs are included in the
>>>> g(r) even though I have specified them as non interacting in the exclusion
>>>> list. I cannot figure out what might be the problem here. Thanks in
>>>> advance.
>>>> >>
>>>> >> Go in the log file (usually inverse.log) and find the last csg_stat
>>>> call (e.g. with "grep csg_stat inverse.log") and post it here.
>>>> >>
>>>> > csg_stat --nt 8 --options settings_nb.xml --top topol.tpr --trj
>>>> traj.xtc --begin 5 --first-frame 0 --cg topology.xml;
>>>> Ok, if you are using a mapping file (--cg option), the exclusion from
>>>> the tpr get mapped out. You will need to add bonds between the atoms
>>>> you want to exclude in mapping file. See here for an example:
>>>>
>>>> https://github.com/votca/csg-tutorials/blob/master/hexane/ibi_all/hexane_cg.xml#L25-L39
>>>> You don't need to do anything with these bonds in the IBI iterations.
>>>>
>>>> Again you can check the exclusions after mapping with csg_dump, e.g.
>>>> $ csg_dump --excl --top topol.tpr --cg topology.xml
>>>>
>>>> Christoph
>>>> >
>>>> >
>>>> >>
>>>> >> Christoph
>>>> >>>
>>>> >>>
>>>> >>>
>>>> >>> Best regards,
>>>> >>> Christianna
>>>> >>>
>>>> >>> On Saturday, December 14, 2019 at 8:52:34 PM UTC+2, Christoph
>>>> Junghans wrote:
>>>> >>>>
>>>> >>>>
>>>> >>>>
>>>> >>>> On Sat, Dec 14, 2019 at 11:27 CHRISTINA-ANNA GATSIOU <
>>>> [email protected]> wrote:
>>>> >>>>>
>>>> >>>>> Hi Christoph,
>>>> >>>>>
>>>> >>>>> My topology.xml does contain exclusions. I have only specified
>>>> nrexcl 3 which I thought should do the job. Do I need to specify exclusions
>>>> in the topology.xml or in the gromacs topology file ?
>>>> >>>>
>>>> >>>> If you are using a tpr file as topology VOTCA will read the
>>>> exclusions from there. If you are using a xml topology exclusions will be
>>>> generated out of the bonds and angles.
>>>> >>>>
>>>> >>>> Just look in inverse.log what topology file is used by csg_stat
>>>> and run csg_dump on it to check the exclusions.
>>>> >>>>
>>>> >>>> Christoph
>>>> >>>>>
>>>> >>>>> Thanks for the prompt response.
>>>> >>>>>
>>>> >>>>> Best regards,
>>>> >>>>> Christianna
>>>> >>>>>
>>>> >>>>> On 14 Dec 2019, at 1:26 AM, Christoph Junghans <[email protected]>
>>>> wrote:
>>>> >>>>>
>>>> >>>>> csg_dump --excl --top <topology_file>
>>>> >>>>>
>>>> >>>>>
>>>> >>>>> --
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>>>>
>>>> >>>>
>>>> >>>> --
>>>> >>>> Christoph Junghans
>>>> >>>> Web: http://www.compphys.de
>>>> >>>
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>>>>
>>>> >>
>>>> >>
>>>> >>
>>>> >> --
>>>> >> Christoph Junghans
>>>> >> Web: http://www.compphys.de
>>>> >
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>>>>
>>>>
>>>>
>>>>
>>>> --
>>>> Christoph Junghans
>>>> Web: http://www.compphys.de
>>>>
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>>> .
>>>
>> --
>> Christoph Junghans
>> Web: http://www.compphys.de
>>
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>


-- 
Christoph Junghans
Web: http://www.compphys.de

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