On Fri, Feb 21, 2020 at 2:26 AM Erez Tamir <[email protected]> wrote:
>
> Dear all,
>
> I'm trying to apply the relative entropy (RE) method, with LJ 12-6 
> interactions, for polymer melt containing 8 bead types.
> My final goal is to reproduce mechanical properties of the atomistic system 
> by CG potentials.
> In order to obtain reasonable initial guess I used the IBI method with 
> pressure correction until the target density and pressure obtained.
> The mechanical behavior is underestimated by the IBI potentials, so I would 
> like to improve them by fitting and optimizing LJ 12-6 potentials with the RE 
> method.
> Each IBI potential was fitted by lj126 function and the obtained parameters 
> are the initial guess.
> I understand that the lj126 functional  in votca is of the form: 
> U(r)=(A/r^12)-(B/r^6), so A=4*ε*σ^12 and B=4*ε*σ^6. Is this correct?
> Following this my RE input for example for ε=2.1Kcal/mol and σ=4.8A is:
>
> #xy
> 0 1256533682
> 1 102737
>
> The following error message appears during iterations:
>
> an error occurred:
> Hessian NOT a positive definite!
> This can be a result of poor initial guess or ill-suited CG potential 
> settings or poor CG sampling.
>
> Is this error due to incorrect input or poor initial guess?
Sikandar knows the details better than me, but I believe this error
usually means you didn't sample long enough in the iteration step and
hence the hessian is not positive definite.

Christoph

> The settings file is attached.
>
> Any help will be appreciated.
>
> Best,
> Erez
>
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-- 
Christoph Junghans
Web: http://www.compphys.de

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