Hello,

The simulation I am running is of a molecule comprising of two identical 
beads held together by a bond. 
I ran the following on my coarse-grained simulation:

csg_inverse --options settings.xml --debug
I have been working on this, and I have been receiving this message:

Appending to existing logfile inverse.log
We are doing Method: ibi
Prepare (dir step_000)
Using initial guess from dist bond.dist.tgt for bond
#############################################################################################################################################
# #
# ERROR: #
# do_external: subscript #
# 
/home/satyend/software/spack/opt/spack/linux-rhel7-broadwell/gcc-9.3.1/votca-csg-2021-vh2kxfbymvudsn3en3wk5xxnie4j73nq/share/votca/scripts/inverse/dist_boltzmann_invert.pl
 
--type bond --kbT 2.47772 --min 1e-10 bond.dist.tgt bond.pot.new.raw.cQ7 #
# (from tags dist invert) failed #
# For details see the logfile 
/tigress/satyend/benzene_simulations/opls-aa/r_cutoff-1.5-org/VOTCA/TwoBead_CG/ibi/inverse.log
 
#
##############################################################################################################################################
Terminated

What could the cause of such an error message be? 
On Tuesday, April 6, 2021 at 8:20:11 AM UTC-4 Christoph Junghans wrote:

>
>
> On Mon, Apr 5, 2021 at 22:56 Satyen Dhamankar <[email protected]> wrote:
>
>> Thank you for your advice, Christoph. 
>>
>> How do you recommend I use harmonic potentials for a CG simulation? I 
>> have the bond.dist.new histogram after I did my mapping, I can use the 
>> modal bond length I obtained from that. However, what can I use as my 
>> spring constant? 
>>
> you can do a boltzmann inversion and then do a quadratic fit.
>
>>
>> Using csg_boltzmann on my bond distribution, I obtained the table at 298 
>> K and set bond, however, the table that was created started at 0.19 nm. My 
>> question is, when performing a boltzmann inversion on the bond 
>> distribution, how do we treat the bins with a height of 0? should the 
>> number at that point simply be inf?
>>
> You will have to do a little bit of post-processing: 
> https://www.votca.org/csg/preparing.html#post-processing-of-the-potential
>
>>
>  
>>
>> This is my mapping file, just to be complete:
>> <cg_molecule>
>> <name>BNZ</name> <!-- the name of the molecule after mapping--> 
>> <ident>UNK</ident> <!-- name of the actual atom --> 
>> <topology>
>> <cg_beads>
>> <cg_bead>
>> <name>B1</name>
>> <type>CG</type>
>> <symmetry>1</symmetry>
>> <mapping>A</mapping> 
>> <beads>
>> 1:UNK:C00 1:UNK:C01 1:UNK:C02 1:UNK:H06 1:UNK:H07 1:UNK:H08 
>> </beads> 
>> </cg_bead>
>>
>> <cg_bead> 
>> <name>B2</name>
>> <type>CG</type>
>> <symmetry>1</symmetry> 
>> <mapping>A</mapping> 
>> <beads>
>> 1:UNK:C03 1:UNK:C04 1:UNK:C05 1:UNK:H09 1:UNK:H0A 1:UNK:H0B
>> </beads>
>> </cg_bead>
>> </cg_beads>
>>
>> <cg_bonded> 
>> <bond>
>> <name>bond</name> 
>> <beads>
>> B1 B2
>> </beads>
>> </bond>
>> </cg_bonded>
>> </topology>
>>
>> <maps>
>> <map>
>> <name>A</name>
>> <weights>12.0110 12.0110 12.0110 1.0080 1.0080 1.0080</weights>
>> </map>
>> </maps>
>> </cg_molecule>
>>
>> I used this file as my mapping file when I executed:
>> csg_boltzmann --top topol.tpr --trj trajectory.trj --cg bezene.xml
>> tab set T 298
>> tab set scale bond 
>> tab table_b1.xvg *:bond:*
>> On Monday, April 5, 2021 at 9:09:15 PM UTC-4 Christoph Junghans wrote:
>>
>>> On Mon, Apr 5, 2021 at 2:20 PM Satyen Dhamankar <[email protected]> 
>>> wrote: 
>>> > 
>>> > Hello, 
>>> > 
>>> > I am performing a coarse-grained simulation of benzene, where I am 
>>> converting C6H6 into two beads. Where each bead is essentially C3H3, and 
>>> they are connected by a bond. 
>>> > 
>>> > I want to perform IBI on this coarse-grained simulation using votca 
>>> and gmx, but I am having some problems. 
>>> > 
>>> > The command I am running is: 
>>> > csg_inverse --options settings.xml 
>>> > 
>>> > I am getting an energy divergence (blows up to infinity) when votca 
>>> runs mdrun. This is the error I see in my inverse.log file: 
>>> > 
>>> > Program: gmx mdrun, version 2019.6 
>>> > Source file: src/gromacs/mdlib/sim_util.cpp (line 752) 
>>> > MPI rank: 1 (out of 6) 
>>> > Fatal error: 
>>> > Step 0: The total potential energy is inf, which is not finite. The LJ 
>>> and 
>>> > electrostatic contributions to the energy are inf and 0, respectively. 
>>> A 
>>> > non-finite potential energy can be caused by overlapping interactions 
>>> in 
>>> > bonded interactions or very large or Nan coordinate values. Usually 
>>> this is 
>>> > caused by a badly- or non-equilibrated initial configuration, 
>>> incorrect 
>>> > interactions or parameters in the topology. 
>>> > For more information and tips for troubleshooting, please check the 
>>> GROMACS 
>>> > website at http://www.gromacs.org/Documentation/Errors 
>>> > 
>>> > I am running a minimization script, but I don't see why energy is 
>>> blowing up. 
>>> > 
>>> > I also am unsure of what the table_b1.xvg and table_a1.xvg files are 
>>> for. I naively got these files from the hexane tutorial. What are these 
>>> files for? How do I make them? 
>>> These two tables are for the bonded interactions, they are just 
>>> boltzmann-inverted tables from the bonded distributions (do that by 
>>> hand or use csg_boltzmann). 
>>> You could also use harmonic potentials as a start to make your life 
>>> easier. 
>>>
>>> Christoph 
>>> > 
>>> > I have attached my grommp.mdp, conf.gro, settings.xml, topol.top and 
>>> tables files. 
>>> > 
>>> > Any advice you have would be appreciated! 
>>> > 
>>> > 
>>> > -- 
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>>>  
>>>
>>>
>>>
>>>
>>> -- 
>>> Christoph Junghans 
>>> Web: http://www.compphys.de 
>>>
>> -- 
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>>  
>> <https://groups.google.com/d/msgid/votca/5b85becb-b3ce-414e-8409-d6f2399e7a81n%40googlegroups.com?utm_medium=email&utm_source=footer>
>> .
>>
> -- 
> Christoph Junghans
> Web: http://www.compphys.de
>

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