Firewire 400 is significantly faster than USB 2 and that goes double for 
firewire 800 so if you plan on booting from your external drive a fair bit and 
you care about performance then perhaps picking up a 2nd hand firewire 
enclosure might be the better option.  The speed of your boot drive has quite a 
big effect on performance which is why many people choose to use SSDs for their 
boot drives these days.

Regards
Ruben

> Hi Peter,
> 
> To answer your question, yes you can use USB2 to boot your MacBookPro. I have 
> a USB 2 'cheap' drive here which I book my MacBook from and although a little 
> bit slow it nonetheless works fine. 
> 
> Please refer to Apple's article at:
> 
> http://support.apple.com/kb/HT1948
> 
> Bear in mind though that USB 2 does not support 'Target Mode', at least that 
> is my understanding. 
> 
> Kind regards,
> Philippe 
> 
> On 12/12/2011, at 1:02 PM, Curtis Peter wrote:
> 
>> Hi
>> So, to carry on from my last email, and being in a regional centre 
>> (Kalgoorlie)
>> I can't get any IDE drives for an old enclosure I have, they say these 
>> drives are too slow and out of date!
>> I can't get a SATA hard drive with a firewire connection, they say these are 
>> out of date being surpassed by USB2 and USB3, which they say is quicker 
>> anyway. (I'm sure I don't have USB3 in my MacBookPro anyway)
>> My question is - can I boot my MacBookPro with USB2?
>> Regards
>> Peter
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