I've written an iPad (only, US-only for now) app, newly in the App Store, that is powered on the back end by web2py.
The marketing website (SquareSpace, not web2py): http://watchup.com Watchup is designed to make it easy and efficient to create a playlist of news videos and watch them. The backend server provides feeds (metadata, not the video streams), user registration, etc, to the app, and also implements an internal curation interface. The one public page on the web2py site is used to host videos when app users tweet them. The implementation is straightforward. Red Hat Enterprise Linux, Apache, MySQL and, of course, web2py. Plus memcached. The host is a Rackspace cloud server; I plan to scale by migrating the database to a dedicated server and replicating application servers as necessary, eventually moving curation to its own server as well. Give it a try; the app is free. http://watchup.com has a link to the app store.

