Dear  All 
Thanks for your response Dr. Thomas director World health organization/ 
Substance Abuse Department. I have read the publication you forwarded to me. 
Indeed drug resistance is a very serious issue in the developing countries. 
It’s very interesting but some of the act does not solve the problem of drug 
resistance. Puting drug user to prison is never a solution but there are better 
methods of solving the drug resistance.  The treatment of Psychosis is the most 
common thing that triggers drugs resistance in the developing nations even 
though few claim that cases of schizophrenia and dementia are uncommon.  During 
my three years of working with AED/ USAID and UNIOM/ WHO outreach program for 
Alcohol, Tobacco and other Substance (drugs) of abuse such cases of 
schizophrenia, dementia and several disorders were commonly found both in the 
villages and towns. We use to attend world health organization/ Substance Abuse 
department  workshops and meeting in Kampala and even in Arua and Koboko drugs 
that are restricted and only be prescribed by Medical doctors and psychiatry 
are been prescribed by CNA and some with lab tech or an body who has drug 
store. The assessment used was based on the WHO and DSM IV definition of 
psychotic disorders.  Schizophrenia is characterized by fundamental distortions 
in thinking and perception and by inappropriate emotions. The disturbance 
involves the most basic functions that give the normal person a feeling of 
individuality, uniqueness and self-direction. Behavior may be seriously 
disturbed during some phases of the disorder leading to adverse social 
consequences. Delusions of strong belief in ideas that are false and without 
any basis of reality and hallucinations commonly auditory for example hearing 
voices are typical   Psychotic features of the disorder.  Psychoactive is a 
substance use causing damage to health. The damage may be physical as in cases 
of hepatitis from the self-administration of injected psychoactive substances 
or mental e.g. episodes of depressive disorder secondary to heavy consumption 
of alcohol. While dependence is a cluster of behavioral, cognitive and 
physiological phenomena that develop after repeated substance use and that 
typically include a strong desire to take the drug, difficulties in controlling 
its use, persisting in its use despite harmful consequences, a higher priority 
given to drug use than to other activities and obligations, increased tolerance 
and sometimes a physical withdrawal state. The dependence syndrome may be 
present for a specific psychoactive substance e.g. tobacco, alcohol or 
diazepam, for a class of substances e.g. opioid drugs or for a wider range of 
pharmacologically different psychoactive substances. In the cause of drug 
resistance includes both of the above not necessarily these alone. Prescribed 
medicine like Benzodiazepines if continued beyond four weeks as a chronic use 
it may induce dependence and withdrawal symptoms which is also a part of drugs 
resistance.  Prescription drugs also play a big role in drug resistance. 
Antidepressants are similarly drugs of abuse if healthcare providers do not 
offer clear information empathetic listening reassurance and psychological 
counseling to patients.  Lithium being considered the medicine of choice in 
long term maintenance phase for bipolar disorder.  Health care providers may 
consider lithium as initial monotherapy but lithium monotherapy is effective 
against both mania and depressive relapse although it is more effective in 
preventing mania.  However healthcare providers have to consider that lithium 
has a narrow therapeutic index and blood levels must be monitored.  It should 
be noted that lithium treatments check thyroid function every six months 
because severe toxic affects cam occur when renal excretion is impaired.  
Vaporate cause a wide range of adverse reactions including gastrointestinal 
pain, benign hepatic transaminase elevations, tremor and sedation. These are 
few I can give as an example that may cause the some of the complications 
including drugs resistance.       
Best wishes,

Arike
 


Date: Wed, 9 Jun 2010 22:39:29 -0700
From: [email protected]
To: [email protected]
Subject: [WestNileNet] THANKS GIVING FOR LETASI SHARONS BORN CANCER TREATMENT






Dear all,
 
We would like to invite you for the thanksgiving function on Sunday 13th June 
2010 at the home of Rosette Obizuyo and Emmanuel Tibaire at Kyaliwajala 
Namugongo.
 
Please read the invitation in the attachment.
 
I do not have the e-mail addresses of our colleagues in The New Vision who 
should be part of this function. Can someone either send me their e-mail 
address so that I forward them this invite, or forward this mail to them.
 
TO ERIMA ROBERT and APOLO ONZOMA
 
Could yu help give direction to Rosettes home.
 
Regards
 
Acidri David Onzima.
                                          
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