Dr. Asiki: Thanks for giving us an insight into the clinical trials process in Uganda.
--- On Fri, 7/19/13, Gershim Asiki <[email protected]> wrote: To: "[email protected]" <[email protected]> > Received: Friday, July 19, 2013, 5:57 AM Dear Anyole, Thanks for sharing your opinion. Just to let you know clinical trials in Uganda are well regulated by professional bodies (Institutional review boards, National drug authority) and Uganda National Council of Science and Technology (which includes clearance from the president's office). Before a trial starts, the president's office notifies the RDC of the district where the research project will be executed to inform them of the planned research and introduce the principal investigators. In these trials participants are given comprehensive information on the studies in a language they best understand before consenting to participate. It is true that sometimes certain unexpected adverse events may occur and participants join knowing something wrong may occur somewhere. There are mechanisms put in place to manage such occurrences. We can not avoid drug trials because of the un-foreseen effects of new drugs because all that we practice in medicine goes through a research process and if we stop rsearch now, then we will not have new interventions in place, yet the current drugs are bound to fail or become less effective at one point. For instance in the field of HIV/AIDS now, we are looking for a vaccine that can prevent HIV transmission and drugs that can cure AIDS because the current interventions are inadequate to curtail the epidemic. These studies are well regulated. Drug companies are not allowed to promote drugs that are not approved for marketing. It is very important to report any suspicious companies that are promoting drugs that have not undergone the research process to the National drug authority or the district health office. As for HPV vaccine, the tests have been completed and it is already found to be safe and effective. The reason for piloting is to assess the uptake of the vaccine by our communities in Uganda and find suitable ways of delivering the vaccination to those who need them. As I pointed out earlier, an effective drug can fail to be rolled out due to socio-cultural beliefs. Pilot programs help us address such challenges of implementation. Thank you for your keen interest on this. Asiki > From: Anyole J > <[email protected]> > To: A Virtual > Network for friends of West Nile <[email protected]> > > Cc: > "[email protected]" > <[email protected]> > Sent: Monday, > 15 July 2013, 18:57 > Subject: > [Kobokonet] Re: [WestNileNet] Fwd: Fw: Province participates > in Human Papillomavirus (HPV) vaccine study > > > > > > > > > > > > > > > > > > > > > > > > Not to take away from > anything whatsoever from this continued effort for better > health for ourselves and our people, I have long been very > suspicious of drug companies operating and doing drug tests > in so called third world countries where regulations are > next to non-existent. I have spoken to a person or two about > this and I was very surprised when one of the people i spoke > to had the same views and had indeed heard of Drug tests > gone bad in certain parts of the world but because there was > no regulation or the power players had been greased, nothing > was ever made of it. > > > just > my opinion. > Anyole > From: Charles Male > <[email protected]> > To: Ezati > Eric <[email protected]>; A Virtual Network for > friends of West Nile <[email protected]> > Sent: Monday, > July 15, 2013 7:40:38 AM > Subject: Re: > [WestNileNet] Fwd: Fw: Province participates in Human > Papillomavirus (HPV) vaccine study > > FYI > ------------------------------------------- > On Sun, 7/14/13, Gershim Asiki <[email protected]> > wrote: > > Subject: Re: [Kobokonet] Fwd: Fw: Province participates in > Human > Papillomavirus (HPV) vaccine study > To: "[email protected]" > <[email protected]> > Received: Sunday, July 14, 2013, 2:23 PM > > Dear Charles, > > Thanks for sharing this interesting study with us. HPV > vaccination is > not yet widely available in Uganda although recently the > vaccination > programme was launched through a collaboration between the > Ugandan > ministry of health > and > north American drug company (Merck Sharpe and Dohme). This > is > targeting 140,000 girls aged 9-12 years in 12 districts. The > plan is > to expand the programme to all districts by 2014. > > One third of women in Uganda are estimated to have the HPV > infection > that is responsible for cancer of the cervix. > > About 3600 women are diagnosed with cervical cancer in > Uganda every year, 2500 of whom die of the disease. This > number is projected to rise to up to 6400 by 2025. > Vaccination against HPV together with regular screening of > women can significantly reduce the risk of this > cancer. > > As kknetters, we should champion the campaign for the > vaccination drive once the vaccine becomes available. > > Asiki > > > On 7/15/13, Ezati Eric <[email protected]> > wrote: > > This vaccine is > already available in Uganda but in > private hospitals and > > targets girls of about 11-15 years who are assumed not > to be sexually active > > at that age given in 3 doses over six months as clearly > stated.The vaccine > > helps to prevent them from getting cancer of cervix at > a letter time. We are > > yet to get communications on public consumption on this > from Ministry of > > health for the benefit of all Ugandans > > > > > > > > Ezati Eric > > > > > > ________________________________ > > From: Charles Male <[email protected]> > > To: Kobokonet Koboko <[email protected]>; > A Virtual Network for > > friends of West Nile <[email protected]> > > Sent: Saturday, > 13 July 2013, 14:42 > > Subject: [WestNileNet] Fwd: Fw: Province participates > in Human > > Papillomavirus (HPV) vaccine study > > > > > > A study that our researchers/scientists might want to > follow closely.... > > > > Dr. Asiki and other medical professional ....Is this > HPV vaccination > > available in Uganda already? > > > > C > > > > ----- Original Message ----- > > From: Prince Edward Island [mailto:[email protected]] > > Sent: Friday, July 12, 2013 05:00 PM > > To: Malé, Charles > > Subject: Province participates in Human Papillomavirus > (HPV) vaccine study > > > > ----------------------------- > > NEWS RELEASE > > ----------------------------- > > > > July 12, 2013 > > > > PROVINCE PARTICIPATES IN HUMAN PAPILLOMAVIRUS (HPV) > VACCINE STUDY > > > > > CHARLOTTETOWN, PEI -- Researchers from > Dalhousie University are > > working with the Prince Edward Island Department of > Health and > > Wellness to conduct a new study of the Human > Papillomavirus (HPV) > > vaccine. > > > > “All girls who received the HPV vaccine > through the school > > vaccination program are being invited to help > researchers with this > > study,” says Chief Public Health Officer, Dr. Heather > Morrison. > > “While it is widely accepted among researchers that > HPV vaccine can > > safely protect against HPV disease and will prevent > cervical cancer, > > it is not known how long this protection lasts, or > whether there is > > any difference in effectiveness between two doses or > three doses of > > HPV vaccine.” > > “We know that HPV causes cervical > cancer, and that the HPV vaccine > > prevents infection from HPV and reduces the risk of > cervical cancer,” > > says Dr. Shelly McNeil, a > lead researcher on the study and infectious > > disease specialist at Dalhousie University and Capital > District Health > > Authority, Halifax. “What we want to determine is how > the two-dose > > schedule given in some provinces compares to the > three-dose schedule > > given here in Prince Edward Island – and we > want to follow girls over > > the long term to see how effective the vaccine has been > over time.” > > Currently, Health Canada has approved a > three-dose schedule of the > > quadrivalent HPV vaccine given over six months. This > three-dose > > schedule is offered by Public Health Nurses in Health > PEI to all girls > > in Grade 6. In some provinces in Canada, the > vaccine is given as a > > two-dose schedule. > > To determine if a two-dose HPV vaccine > schedule provides equivalent > > protection, the Quadrivalent HPV Vaccine Evaluation > Study (QUEST) will > > > follow more than 8,500 teenage girls recruited from British > Columbia, > > Alberta, Quebec and the Maritimes for up to 10 years. > The study will > > assess risk factors, frequency of infection with HPV, > and the level of > > protection provided by two doses of vaccine compared to > three doses. > > “Letters are being sent to Prince > Edward Island girls who received > > three doses of HPV vaccine since 2007,” says Dr. > Morrison. “Over the > > next several months, all girls who received the HPV > immunization in > > school are being invited to assist in finding out the > difference the > > vaccine makes.” > > The Prince Edward Island HPV immunization > program has been offered > > since the 2007/2008 school year. > > QUEST builds on earlier HPV vaccine > research. In 2006, research > > conducted in Canada measured the short-term immune > response of a > > two-dose > HPV vaccine. QUEST aims to determine if this > protection is > > maintained over a longer term. Dr. Morrison adds, > “This study will > > help optimize our HPV vaccine dosing schedule to ensure > the current > > and future health and well-being of Islanders.” > > > > > > -30- > > > > For more information, contact Mary Moszynski, Health > and Wellness by > > email at [email protected] > or phone (902) 368-5610. > > > > To change your subscription preferences visit > www.gov.pe.ca/mailinglists. > > > > > > > > To remove yourself from this email list, please go to > the following > > address in your web browser: > > > www.gov.pe.ca/mailinglists/remove.php3?un=646090&ln=1&email=charles.male%40tbs-sct.gc.ca > > Pour supprimer votre nom de cette liste de courriels, > veuillez vous > > rendre à > l'adresse suivante dans votre navigateur: > > > www.gov.pe.ca/mailinglists/remove.php3?un=646090&ln=1&email=charles.male%40tbs-sct.gc.ca > > _______________________________________________ > > WestNileNet mailing list > > [email protected] > > http://orion.kym.net/mailman/listinfo/westnilenet > > > > WestNileNet is generously hosted by INFOCOM http://www.infocom.co.ug/ > > > > The above comments and data are owned by whoever posted > them (including > > attachments if any). The List's Host is not > responsible for them in any way. > > > _______________________________________________ > _______________________________________________ > WestNileNet mailing list > [email protected] > http://orion.kym.net/mailman/listinfo/westnilenet > > WestNileNet is generously hosted by INFOCOM http://www.infocom.co.ug/ > > The above comments and data are owned by whoever posted them > (including attachments if any). The List's Host is not > responsible for them in any way. > _______________________________________________ > > > > > > > > > > > > > > > > > > > > > > __._,_.___ > > > > > > > > > Reply > via web post > > > > Reply to sender > > > > Reply to group > > > Start a New > Topic > > > Messages in this > topic > (3) > > > > > > > > > > > > > Recent > Activity: > > > > > > Visit Your Group > > > > > > > > Switch to: Text-Only, Daily Digest • Unsubscribe • Terms of Use • Send us > Feedback > > > > > > > > > > > > > > > > > > > > . > > > > > > __,_._,___ > > > > > > > > > > > > > > > > _______________________________________________ WestNileNet mailing list [email protected] http://orion.kym.net/mailman/listinfo/westnilenet WestNileNet is generously hosted by INFOCOM http://www.infocom.co.ug/ The above comments and data are owned by whoever posted them (including attachments if any). The List's Host is not responsible for them in any way. _______________________________________________
