I've been running a similar setup on Gentoo Linux.

MySQL
dbmail
postfix
spamassassin
fuzzyOCR
amavisd-new
clamav

It all just works, its stable and not too hard to manage.  You won't 
find a cool control panel.

These are the technologies that Barracuda uses in their "appliances."




On 3/24/2010 4:53 PM, Justin Wilson wrote:
>      Chuck turned me on to PurpleHat a month of so ago. We are in the process
> of testing it on some domains.  Most of the packages within it are ones that
> continually get updated.
>
>      This might help:
> http://www.purplehat.org/?page_id=4
>
> BTW: We are running it in a Virtual Machine and so far so good.
>    



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