\documentclass[a4paper,11pt]{article}

\usepackage{ifxetex}
\RequireXeTeX
\usepackage{xltxtra}

\setlength{\parindent}{0mm}

\newcommand\ked{\catcode`\^=11
           \catcode`\~=11
           \fontspec[Script=Devanagari,Mapping=itrans-dvn]{Sanskrit 2003}}

\begin{document}

{\ked
OM ||  nArAyaNaM suraguruM jagadekanAthaM \\
bhaktapriyaM sakalalokanamaskR^itaM cha | \\
traiguNyavarjitamajaM vibhumAdyamIshaM \\
vande bhavaghnamamarAsurasiddhavandyam.h  ||
}

\end{document}