And another shot:
\documentclass{article}
\usepackage{fontspec}
\setmainfont[Numbers={OldStyle,Proportional}]{Adobe Garamond Pro}
\newfontfamily\fnmarkfont{Myriad Pro}
\makeatletter
\renewcommand...@makefnmark}{%
\mbox{\textsuperscript{\fnmarkfo...@thefnmark}}}
\makeatother
\begin{document}
Test\footnote{Some text.}
Test\footnote{Some text.}
Test\footnote{Some text.}
Test\footnote{Some text.}
Test\footnote{Some text.}
Test\footnote{Some text.}
Test\footnote{Some text.}
Test\footnote{Some text.}
Test\footnote{Some text.}
\end{document}
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